An overview of in silico vaccine design against different pathogens and cancer
Introduction Due to overcome the hardness of the vaccine design, computational
vaccinology is emerging widely. Prediction of T cell and B cell epitopes, antigen processing …
vaccinology is emerging widely. Prediction of T cell and B cell epitopes, antigen processing …
Current methods for the prediction of T‐cell epitopes
T‐cell epitopes are specific peptide sequences derived from foreign or own proteins that can
initiate an immune response and which are recognized by specific T‐cells when displayed …
initiate an immune response and which are recognized by specific T‐cells when displayed …
Prioritization of potential vaccine candidates and designing a multiepitope-based subunit vaccine against multidrug-resistant Salmonella Typhi str. CT18: A subtractive …
Salmonella enterica serovar Typhi (S. Typhi), a causative agent of typhoid fever, is a Gram-
negative, human-restricted pathogen that causes significant morbidity and mortality …
negative, human-restricted pathogen that causes significant morbidity and mortality …
Immunoinformatics approach in designing epitope-based vaccine against meningitis-inducing bacteria (Streptococcus pneumoniae, Neisseria meningitidis, and …
Meningitis infection is one of the major threats during Hajj season in Mecca. Meningitis
vaccines are available, but their uses are limited in some countries due to religious reasons …
vaccines are available, but their uses are limited in some countries due to religious reasons …
An Immunoinformatics-Based Study of Mycobacterium tuberculosis Region of Difference-2 Uncharacterized Protein (Rv1987) as a Potential Subunit Vaccine Candidate for …
Mycobacterium tuberculosis (Mtb) is the pathogen that causes tuberculosis and develops
resistance to many of the existing drugs. The sole licensed TB vaccine, BCG, is unable to …
resistance to many of the existing drugs. The sole licensed TB vaccine, BCG, is unable to …
Genome-based approaches to develop epitope-driven subunit vaccines against pathogens of infective endocarditis
Infective endocarditis (IE) has emerged as a public health problem due to changes in the
etiologic spectrum and due to involvement of resistant bacterial strains with increased …
etiologic spectrum and due to involvement of resistant bacterial strains with increased …
Recombinant NAD-dependent SIR-2 Protein of Leishmania donovani: Immunobiochemical Characterization as a Potential Vaccine against Visceral Leishmaniasis
RK Baharia, R Tandon, T Sharma… - PLoS neglected …, 2015 - journals.plos.org
Background The development of a vaccine conferring long-lasting immunity remains a
challenge against visceral leishmaniasis (VL). Immunoproteomic characterization of …
challenge against visceral leishmaniasis (VL). Immunoproteomic characterization of …
In silico design of small peptides antagonist against leptin receptor for the treatment of obesity and its associated immune-mediated diseases
Excess adiposity in obese inhibits negatively impacts immune function and host defence.
Obesity is characterized by a state of low-grade, chronic inflammation in addition to …
Obesity is characterized by a state of low-grade, chronic inflammation in addition to …
Discovery of T-cell driven subunit vaccines from Zika virus genome: an immunoinformatics approach
D Pradhan, M Yadav, R Verma, NS Khan… - Interdisciplinary …, 2017 - Springer
The recent outbreaks of Zika virus and the absence of a specific therapy have necessitated
to identify T-cell-stimulating antigenic peptides as potential subunit vaccine candidates. The …
to identify T-cell-stimulating antigenic peptides as potential subunit vaccine candidates. The …
[HTML][HTML] Comprehensive structural and functional analysis of hVEGFR1: Insights into phosphorylation, molecular interactions, and potential inhibitors through docking …
Abstract Vascular Endothelial Growth Factor Receptor 1 (VEGFR1), is an enzyme with
tyrosine kinase activity that plays a pivotal role in angiogenesis, the process of new blood …
tyrosine kinase activity that plays a pivotal role in angiogenesis, the process of new blood …