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Synthetic microbial communities (SynComs) of the human gut: design, assembly, and applications
The human gut harbors native microbial communities, forming a highly complex ecosystem.
Synthetic microbial communities (SynComs) of the human gut are an assembly of …
Synthetic microbial communities (SynComs) of the human gut are an assembly of …
Reconstructing organisms in silico: genome-scale models and their emerging applications
Escherichia coli is considered to be the best-known microorganism given the large number
of published studies detailing its genes, its genome and the biochemical functions of its …
of published studies detailing its genes, its genome and the biochemical functions of its …
Addressing global ruminant agricultural challenges through understanding the rumen microbiome: past, present, and future
The rumen is a complex ecosystem composed of anaerobic bacteria, protozoa, fungi,
methanogenic archaea and phages. These microbes interact closely to breakdown plant …
methanogenic archaea and phages. These microbes interact closely to breakdown plant …
A metabolic modeling platform for the computation of microbial ecosystems in time and space (COMETS)
Genome-scale stoichiometric modeling of metabolism has become a standard systems
biology tool for modeling cellular physiology and growth. Extensions of this approach are …
biology tool for modeling cellular physiology and growth. Extensions of this approach are …
Challenges in microbial ecology: building predictive understanding of community function and dynamics
The importance of microbial communities (MCs) cannot be overstated. MCs underpin the
biogeochemical cycles of the earth's soil, oceans and the atmosphere, and perform …
biogeochemical cycles of the earth's soil, oceans and the atmosphere, and perform …
Genome-scale metabolic modeling enables in-depth understanding of big data
Genome-scale metabolic models (GEMs) enable the mathematical simulation of the
metabolism of archaea, bacteria, and eukaryotic organisms. GEMs quantitatively define a …
metabolism of archaea, bacteria, and eukaryotic organisms. GEMs quantitatively define a …
Systematic assessment of secondary bile acid metabolism in gut microbes reveals distinct metabolic capabilities in inflammatory bowel disease
Background The human gut microbiome performs important functions in human health and
disease. A classic example for host-gut microbial co-metabolism is host biosynthesis of …
disease. A classic example for host-gut microbial co-metabolism is host biosynthesis of …
Costless metabolic secretions as drivers of interspecies interactions in microbial ecosystems
Metabolic exchange mediates interactions among microbes, hel** explain diversity in
microbial communities. As these interactions often involve a fitness cost, it is unclear how …
microbial communities. As these interactions often involve a fitness cost, it is unclear how …
Metabolic resource allocation in individual microbes determines ecosystem interactions and spatial dynamics
The interspecies exchange of metabolites plays a key role in the spatiotemporal dynamics of
microbial communities. This raises the question of whether ecosystem-level behavior of …
microbial communities. This raises the question of whether ecosystem-level behavior of …
[كتاب][B] Nonlinear programming: concepts, algorithms, and applications to chemical processes
LT Biegler - 2010 - SIAM
Chemical engineering applications have been a source of challenging optimization
problems for over 50 years. For many chemical process systems, detailed steady state and …
problems for over 50 years. For many chemical process systems, detailed steady state and …