Altered brain responses to alcohol-associated stimuli are a neural hallmark of alcohol-use
disorder (AUD) and a promising target for pharmacotherapy. However, findings in cue …

Background Individual differences in the subjective experience of the pharmacological
effects of alcohol have long been implicated in the likelihood that one will drink heavily and …

In a group of 831 participants from the general population in the Human Connectome
Project, smokers exhibited low overall functional connectivity, and more specifically of the …

Baclofen has been suggested as a potential pharmacotherapy for alcohol use disorder, but
the clinical data are conflicting. Here we investigated the biobehavioral effects of baclofen in …

Background Subjective response to alcohol has been examined as a marker of alcoholism
risk. The A 118 G single‐nucleotide polymorphism (SNP) of the mu‐opioid receptor …

This review evaluates the viability of delayed reward discounting (DRD), an index of how
much an individual devalues a future reward based on its delay in time, for genetically …

Abstract Effects of cue exposure and alcohol consumption (eg, priming doses) on craving for
alcohol have been examined in largely separate literature, limiting what is known about their …

Alcohol exposed pregnancy (AEP) is a leading cause of preventable birth defects. While
randomized controlled trials (RCTs) have shown that multi-session motivational interviewing …

The endogenous opioid system has been implicated in the pathophysiology of alcoholism
as it modulates the neurobehavioral effects of alcohol. A variant in the mu opioid receptor …

Studies have implicated neuroinflammatory processes in the pathophysiology of various
psychiatric conditions, including addictive disorders. Neuroimmune signaling represents an …