Featured Application The specific application of this review article is for the advancement of
commercially translatable technologies in the field of whole organ engineering. Abstract End …

Fecal incontinence (FI) is defined as the involuntary loss or passage of solid or liquid stool in
patients. It is important to point out that the definition of FI does not include flatus …

Neurointestinal diseases represent a significant challenge in clinical management with
current palliative approaches failing to overcome disease and treatment-related morbidity …

Anal sphincter incontinence is a chronic disease, which dramatically impairs quality of life
and induces high costs for the society. Surgery, considered as the best curative option …

Purpose: The aim of this study was to develop a nomogram for predicting the probability of
postoperative soiling in patients aged greater than 1 year operated for Hirschsprung disease …

Background Utilization of autologous stem cells has been proposed for the treatment of anal
incontinence despite a lack of understanding of their mechanism of action and of the …

Fecal incontinence is the involuntary passage or the incapacity to control the release of fecal
matter through the anus. It is a condition that significantly impairs quality of life in those that …

La incontinencia fecal es el paso involuntario o la incapacidad de controlar la descarga de
materia fecal a través del ano, siendo una condición que deteriora significativamente la …

Organ-specific activity is directly dependent on the functional organization of its fundamental
building blocks including the resident/infiltrating cell populations and tissue-specific ECM …

The success of a biomedical device is highly dependent on the material used, which should
be noncytotoxic, nonimmunogenic and minimally proinflammatory. 1, 2 Ranging from …