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Redox biology of exercise: an integrative and comparative consideration of some overlooked issues
The central aim of this review is to address the highly multidisciplinary topic of redox biology
as related to exercise using an integrative and comparative approach rather than focusing …
as related to exercise using an integrative and comparative approach rather than focusing …
Natural tolerance to ischemia and hypoxemia in diving mammals: a review
Reperfusion injury follows ischemia/reperfusion events occurring during myocardial
infarction, stroke, embolism, and other peripheral vascular diseases. Decreased blood flow …
infarction, stroke, embolism, and other peripheral vascular diseases. Decreased blood flow …
Genes lost during the transition from land to water in cetaceans highlight genomic changes associated with aquatic adaptations
The transition from land to water in whales and dolphins (cetaceans) was accompanied by
remarkable adaptations. To reveal genomic changes that occurred during this transition, we …
remarkable adaptations. To reveal genomic changes that occurred during this transition, we …
Evolutionary impacts of purine metabolism genes on mammalian oxidative stress adaptation
Many mammals risk damage from oxidative stress stemming from frequent dives (ie, cycles
of ischemia/reperfusion and hypoxia/reoxygenation), high altitude and subterranean …
of ischemia/reperfusion and hypoxia/reoxygenation), high altitude and subterranean …
Ancient convergent losses of Paraoxonase 1 yield potential risks for modern marine mammals
Mammals diversified by colonizing drastically different environments, with each transition
yielding numerous molecular changes, including losses of protein function. Though not …
yielding numerous molecular changes, including losses of protein function. Though not …
Hypoxia exposure blunts angiogenic signaling and upregulates the antioxidant system in endothelial cells derived from elephant seals
Background Elephant seals exhibit extreme hypoxemic tolerance derived from repetitive
hypoxia/reoxygenation episodes they experience during diving bouts. Real-time …
hypoxia/reoxygenation episodes they experience during diving bouts. Real-time …
Neonatal outcomes of waterbirth: a systematic review and meta-analysis
Introduction In 2015, 9% of babies born in the UK were delivered underwater. Waterbirth is
increasing in popularity, despite uncertainty regarding its safety for neonates. This …
increasing in popularity, despite uncertainty regarding its safety for neonates. This …
How widespread is preparation for oxidative stress in the animal kingdom?
It is well known that many anoxia/hypoxia tolerant species when exposed to anoxia/hypoxia
respond by increasing the activity/expression of antioxidant enzymes and/or glutathione …
respond by increasing the activity/expression of antioxidant enzymes and/or glutathione …
Co** with physiological oxidative stress: a review of antioxidant strategies in seals
While diving, seals are exposed to apnea-induced hypoxemia and repetitive cycles of
ischemia/reperfusion. While on land, seals experience sleep apnea, as well as prolonged …
ischemia/reperfusion. While on land, seals experience sleep apnea, as well as prolonged …
The bottlenose dolphin (Tursiops truncatus): a novel model for studying healthy arterial aging
Endothelial function declines with aging and independently predicts future cardiovascular
disease (CVD) events. Diving also impairs endothelial function in humans. Yet, dolphins …
disease (CVD) events. Diving also impairs endothelial function in humans. Yet, dolphins …