Background Poly (lactic acid)(PLA) and poly (lactic-co-glycolic acid)(PLGA) are among the
well-documented FDA-approved polymers used for the preparation of safe and effective …

The targeted and efficiency-oriented delivery of (therapeutic) nucleic acids raises hope for
successful gene therapy, ie, for the local and individual treatment of acquired and inherited …

Gene therapy is a promising strategy for the treatment of monogenic disorders. Non-viral
gene delivery systems including lipid-based DNA therapeutics offer the opportunity to …

Gene therapy represents a promising cancer treatment featuring high efficacy and limited
side effects, but it is stymied by a lack of safe and efficient gene-delivery vectors. Cationic …

Despite the extensive research on therapeutic delivery, many problems still exist on how to
develop a proper platform (a carrier) that can deliver drugs/nucleic acids to specific sites of …

Gene therapy using nucleic acids has many clinical applications for the treatment of
diseases with a genetic origin as well as for the development of innovative vaccine …

A bird's eye view is now demanded in the area of cancer research to suppress the suffering
of cancer patient and mediate the lack of treatment related to chemotherapy. Chemotherapy …

The meaning of gene therapy is the delivery of DNA or RNA to cells for the treatment or
prevention of genetic disorders. The success rate of gene therapy depends on the …

Over the past few decades, gene therapy has gained immense importance in medical
research as a promising treatment strategy for diseases such as cancer, AIDS, Alzheimer's …

Gene transfer methods are promising in the field of gene therapy. Current methods for gene
transfer include three major groups: viral, physical and chemical methods. This review …