Cell migration is fundamental to establishing and maintaining the proper organization of
multicellular organisms. Morphogenesis can be viewed as a consequence, in part, of cell …

Desmosomes are intercellular junctions of epithelia and cardiac muscle. They resist
mechanical stress because they adopt a strongly adhesive state in which they are said to be …

An essential feature of a healed wound is the restoration of an intact epidermal barrier
through wound epithelialization, also known as re-epithelialization. The directed migration of …

In the wound healing process, the morphology of keratinocytes at the wound edge
temporarily changes to a spindle morphology, which is thought to occur due to an epithelial …

Cadherins are a superfamily of cell surface glycoproteins whose ectodomains contain
multiple repeats of β-sandwich extracellular cadherin (EC) domains that adopt a similar fold …

Cutaneous wound healing occurs in distinct yet overlap** steps with the end goal of
reforming a stratified epithelium to restore epidermal barrier function. A key component of …

Desmosomes are highly specialized anchoring junctions that link intermediate filaments to
sites of intercellular adhesion, thus facilitating the formation of a supracellular scaffolding …

The desmosome is a cell–cell adhesive junction that provides integrity and mechanical
resistance to tissues through its attachment to the intermediate filament cytoskeleton …

Desmosomes are adhesive intercellular junctions that mechanically integrate adjacent cells
by coupling adhesive interactions mediated by desmosomal cadherins to the intermediate …

Intercellular anchoring junctions are highly specialized regions of the plasma membrane
where members of the cadherin family of transmembrane adhesion molecules on opposing …