Abstract The 3, 3′‐disubstituted oxindole structural motif is a prominent feature in many
alkaloid natural products, which include all kinds of tetrasubstituted carbon stereocenters …

In studying the evolution of organic chemistry and gras** its essence, one comes quickly
to the conclusion that no other type of reaction plays as large a role in sha** this domain …

Asymmetric multicomponent reactions involve the preparation of chiral compounds by the
reaction of three or more reagents added simultaneously. This kind of addition and reaction …

The carboxylation of low‐value commodity chemicals to provide higher‐value carboxylic
acids is of significant interest. Recently alternative routes to the traditional hydroformylation …

Most of the efforts of organic chemists have been directed to the development of creative
strategies to build carbon–carbon and carbon–heteroatom bonds in a predictable and …

Described is an efficient catalytic asymmetric intermolecular C C bond‐formation process
to generate acyclic all‐carbon quaternary stereocenters. The reactions overcome the …

Our ability to access the more complex members of the cyclotryptamine family of alkaloids,
and to exploit their disparate biological activities, is limited by the synthetic challenge posed …

Quaternary stereocenters are a particular challenge for stereoselective synthesis. With a
central view on this specific structural issue, selected examples from the recent literature are …

All‐carbon quaternary stereocenters have posed significant challenges in the synthesis of
complex natural products. These important structural motifs have inspired the development …

The family of allylation reactions developed by Tsuji in the 1980s are capable of generating
tertiary and quaternary carbon stereocenters from several synthetic precursors. Despite the …