Recent trends in protein and peptide-based biomaterials for advanced drug delivery

A Varanko, S Saha, A Chilkoti - Advanced drug delivery reviews, 2020 - Elsevier
Engineering protein and peptide-based materials for drug delivery applications has gained
momentum due to their biochemical and biophysical properties over synthetic materials …

Elastin-like polypeptides for biomedical applications

AK Varanko, JC Su, A Chilkoti - Annual review of biomedical …, 2020 - annualreviews.org
Elastin-like polypeptides (ELPs) are stimulus-responsive biopolymers derived from human
elastin. Their unique properties—including lower critical solution temperature phase …

The pathway to intelligence: using stimuli‐responsive materials as building blocks for constructing smart and functional systems

X Zhang, L Chen, KH Lim, S Gonuguntla… - Advanced …, 2019 - Wiley Online Library
Abstract Systems that are intelligent have the ability to sense their surroundings, analyze,
and respond accordingly. In nature, many biological systems are considered intelligent (eg …

Biopolymer-based nanoparticles for drug/gene delivery and tissue engineering

SK Nitta, K Numata - International journal of molecular sciences, 2013 - mdpi.com
There has been a great interest in application of nanoparticles as biomaterials for delivery of
therapeutic molecules such as drugs and genes, and for tissue engineering. In particular …

Selenium nanomaterials: an overview of recent developments in synthesis, properties and potential applications

S Chaudhary, A Umar, SK Mehta - Progress in Materials Science, 2016 - Elsevier
Advances in science and nanotechnology have facilitated the development of new methods
for the preparation of pure selenium as selenium nanomaterials. They offer remarkable …

Quantification of the effects of chain length and concentration on the thermal behavior of elastin-like polypeptides

DE Meyer, A Chilkoti - Biomacromolecules, 2004 - ACS Publications
At a specific temperature, elastin-like polypeptides (ELPs) undergo a sharp solubility
transition that can be exploited in a variety of applications in biotechnology and medicine …

Elastin‐like polypeptides: biomedical applications of tunable biopolymers

SR MacEwan, A Chilkoti - Peptide Science: Original Research …, 2010 - Wiley Online Library
Artificial repetitive polypeptides have grown in popularity as a bioinspired alternative to
synthetic polymers. The genetically encoded synthesis, monodispersity, potential lack of …

Genetically encoded synthesis of protein-based polymers with precisely specified molecular weight and sequence by recursive directional ligation: examples from the …

DE Meyer, A Chilkoti - Biomacromolecules, 2002 - ACS Publications
We report a new strategy for the synthesis of genes encoding repetitive, protein-based
polymers of specified sequence, chain length, and architecture. In this stepwise approach …

Applications of elastin-like polypeptides in drug delivery

SR MacEwan, A Chilkoti - Journal of Controlled Release, 2014 - Elsevier
Elastin-like polypeptides (ELPs) are biopolymers inspired by human elastin. Their lower
critical solution temperature phase transition behavior and biocompatibility make them …

Hydrogels as smart biomaterials

J Kopeček, J Yang - Polymer international, 2007 - Wiley Online Library
Hydrogels were the first biomaterials rationally designed for human use. Beginning with the
pioneering work of Wichterle and Lím on three‐dimensional polymers that swell in water, we …