Microbiome datasets are compositional: and this is not optional

GB Gloor, JM Macklaim, V Pawlowsky-Glahn… - Frontiers in …, 2017 - frontiersin.org
Datasets collected by high-throughput sequencing (HTS) of 16S rRNA gene amplimers,
metagenomes or metatranscriptomes are commonplace and being used to study human …

[HTML][HTML] Network analysis methods for studying microbial communities: A mini review

MS Matchado, M Lauber, S Reitmeier… - Computational and …, 2021 - Elsevier
Microorganisms including bacteria, fungi, viruses, protists and archaea live as communities
in complex and contiguous environments. They engage in numerous inter-and intra …

NetCoMi: network construction and comparison for microbiome data in R

S Peschel, CL Müller, E Von Mutius… - Briefings in …, 2021 - academic.oup.com
Motivation Estimating microbial association networks from high-throughput sequencing data
is a common exploratory data analysis approach aiming at understanding the complex …

Understanding sequencing data as compositions: an outlook and review

TP Quinn, I Erb, MF Richardson, TM Crowley - Bioinformatics, 2018 - academic.oup.com
Motivation Although seldom acknowledged explicitly, count data generated by sequencing
platforms exist as compositions for which the abundance of each component (eg gene or …

A field guide for the compositional analysis of any-omics data

TP Quinn, I Erb, G Gloor, C Notredame… - …, 2019 - academic.oup.com
Background Next-generation sequencing (NGS) has made it possible to determine the
sequence and relative abundance of all nucleotides in a biological or environmental …

Gut microbiome composition is predictive of incident type 2 diabetes in a population cohort of 5,572 Finnish adults

MO Ruuskanen, PP Erawijantari, AS Havulinna… - Diabetes …, 2022 - Am Diabetes Assoc
OBJECTIVE To examine the previously unknown long-term association between gut
microbiome composition and incident type 2 diabetes in a representative population cohort …

ATTED-II v11: a plant gene coexpression database using a sample balancing technique by subagging of principal components

T Obayashi, H Hibara, Y Kagaya, Y Aoki… - Plant and Cell …, 2022 - academic.oup.com
Abstract ATTED-II (https://atted. jp) is a gene coexpression database for nine plant species
based on publicly available RNAseq and microarray data. One of the challenges in …

Single-cell network biology for resolving cellular heterogeneity in human diseases

J Cha, I Lee - Experimental & molecular medicine, 2020 - nature.com
Understanding cellular heterogeneity is the holy grail of biology and medicine. Cells
harboring identical genomes show a wide variety of behaviors in multicellular organisms …

The functional evolution of termite gut microbiota

J Arora, Y Kinjo, J Šobotník, A Buček, C Clitheroe… - Microbiome, 2022 - Springer
Background Termites primarily feed on lignocellulose or soil in association with specific gut
microbes. The functioning of the termite gut microbiota is partly understood in a handful of …

Species-level analysis of human gut microbiota with metataxonomics

J Yang, J Pu, S Lu, X Bai, Y Wu, D **… - Frontiers in …, 2020 - frontiersin.org
The current understanding of human gut microbial community is mainly limited to taxonomic
features at the genus level. Here, we examined the human gut microbial community at the …