Perioperative nutrition: Recommendations from the ESPEN expert group

DN Lobo, L Gianotti, A Adiamah, R Barazzoni… - Clinical nutrition, 2020 - Elsevier
Background & aims Malnutrition has been recognized as a major risk factor for adverse
postoperative outcomes. The ESPEN Symposium on perioperative nutrition was held in …

Disuse-induced skeletal muscle atrophy in disease and nondisease states in humans: mechanisms, prevention, and recovery strategies

EA Nunes, T Stokes, J McKendry… - … of Physiology-Cell …, 2022 - journals.physiology.org
Decreased skeletal muscle contractile activity (disuse) or unloading leads to muscle mass
loss, also known as muscle atrophy. The balance between muscle protein synthesis (MPS) …

Protein ingestion to stimulate myofibrillar protein synthesis requires greater relative protein intakes in healthy older versus younger men

DR Moore, TA Churchward-Venne… - … Series A: Biomedical …, 2015 - academic.oup.com
Background. Adequate protein ingestion-mediated stimulation of myofibrillar protein
synthesis (MPS) is required to maintain skeletal muscle mass. It is currently unknown what …

Modifiable and non-modifiable risk factors for COVID-19, and comparison to risk factors for influenza and pneumonia: results from a UK Biobank prospective cohort …

FK Ho, CA Celis-Morales, SR Gray, SV Katikireddi… - BMJ open, 2020 - bmjopen.bmj.com
Objectives We aimed to investigate demographic, lifestyle, socioeconomic and clinical risk
factors for COVID-19, and compared them to risk factors for pneumonia and influenza in UK …

Protein consumption and the elderly: what is the optimal level of intake?

JI Baum, IY Kim, RR Wolfe - Nutrients, 2016 - mdpi.com
Maintaining independence, quality of life, and health is crucial for elderly adults. One of the
major threats to living independently is the loss of muscle mass, strength, and function that …

Aging is accompanied by a blunted muscle protein synthetic response to protein ingestion

BT Wall, SH Gorissen, B Pennings, R Koopman… - PloS one, 2015 - journals.plos.org
Purpose Progressive loss of skeletal muscle mass with aging (sarcopenia) forms a global
health concern. It has been suggested that an impaired capacity to increase muscle protein …

Muscle atrophy induced by mechanical unloading: mechanisms and potential countermeasures

Y Gao, Y Arfat, H Wang, N Goswami - Frontiers in physiology, 2018 - frontiersin.org
Prolonged periods of skeletal muscle inactivity or mechanical unloading (bed rest, hindlimb
unloading, immobilization, spaceflight and reduced step) can result in a significant loss of …

Skeletal muscle atrophy during short-term disuse: implications for age-related sarcopenia

BT Wall, ML Dirks, LJC Van Loon - Ageing research reviews, 2013 - Elsevier
Situations such as the recovery from injury and illness can lead to enforced periods of
muscle disuse or unloading. Such circumstances lead to rapid skeletal muscle atrophy, loss …

Live strong and prosper: the importance of skeletal muscle strength for healthy ageing

M McLeod, L Breen, DL Hamilton, A Philp - Biogerontology, 2016 - Springer
Due to improved health care, diet and infrastructure in developed countries, since 1840 life
expectancy has increased by approximately 2 years per decade. Accordingly, by 2050, a …

Two weeks of reduced activity decreases leg lean mass and induces “anabolic resistance” of myofibrillar protein synthesis in healthy elderly

L Breen, KA Stokes… - The Journal of …, 2013 - academic.oup.com
Background: Alterations in muscle protein metabolism underlie age-related muscle atrophy.
During periods of muscle disuse, muscle protein synthesis is blunted, and muscle atrophy …