Alpha glucosidase inhibitory activities of plants with focus on common vegetables

ST Assefa, EY Yang, SY Chae, M Song, J Lee, MC Cho… - Plants, 2019 - mdpi.com
Type-2 diabetes mellitus is one of the most prevalent metabolic diseases in the world, and is
characterized by hyperglycemia (ie, high levels of glucose in the blood). Alpha-glucosidases …

Emerging strategies for the activity assay and inhibitor screening of alpha-glucosidase

X Zhang, G Li, D Wu, Y Yu, N Hu, H Wang, X Li… - Food & function, 2020 - pubs.rsc.org
The high incidence of diabetes mellitus has caused widespread concern around the world,
and has quickly become one of the most prevalent and costly chronic diseases. Alpha …

Screening for potential α-glucosidase and α-amylase inhibitory constituents from selected Vietnamese plants used to treat type 2 diabetes

BTD Trinh, D Staerk, AK Jäger - Journal of ethnopharmacology, 2016 - Elsevier
Ethnopharmacological relevance The 18 plant species investigated in this study have been
used as herbal antidiabetic remedies in Vietnamese traditional medicines. This study aimed …

Inhibition of α-glucosidase activity by selected edible seaweeds and fucoxanthin

N Zaharudin, D Staerk, LO Dragsted - Food Chemistry, 2019 - Elsevier
A 5 mg/mL solution of water, methanol and acetone extracts of seaweeds were used for α-
glucosidase inhibition assay hyphenated with high performance liquid chromatography …

Combined LC/UV/MS and NMR strategies for the dereplication of marine natural products

I Pérez-Victoria, J Martín, F Reyes - Planta medica, 2016 - thieme-connect.com
Drug discovery from marine natural products has experienced a revival since the beginning
of this century. To be successful in this field, rapid dereplication (identification of already …

Antidiabetic xanthones with α-glucosidase inhibitory activities from an endophytic Penicillium canescens

A Malik, H Ardalani, S Anam, LM McNair… - Fitoterapia, 2020 - Elsevier
Worldwide, 463 million people are affected by diabetes of which the majority is diagnosed
with Type 2 Diabetes (T2D). T2D can ultimately lead to retinopathy, nephropathy, nerve …

Dual high-resolution α-glucosidase and PTP1B inhibition profiling combined with HPLC-PDA-HRMS-SPE-NMR analysis for the identification of potentially antidiabetic …

C Liang, L Kjaerulff, PR Hansen… - Journal of Natural …, 2021 - ACS Publications
Thirteen previously undescribed chromene meroterpenoids, capitachromenic acids A–M (3–
6, 7a, 7b, 8a, 8b, 9a, 9b, 10a, 10b, and 11b), were identified from an ethyl acetate extract of …

Edible seaweed as future functional food: Identification of α-glucosidase inhibitors by combined use of high-resolution α-glucosidase inhibition profiling and HPLC …

B Liu, KT Kongstad, S Wiese, AK Jäger, D Staerk - Food chemistry, 2016 - Elsevier
Crude chloroform, ethanol and acetone extracts of nineteen seaweed species were
screened for their antioxidant and α-glucosidase inhibitory activity. Samples showing more …

Evaluation of the antidiabetic potential of Psidium guajava L.(Myrtaceae) using assays for α-glucosidase, α-amylase, muscle glucose uptake, liver glucose production …

MN Beidokhti, HM Eid, MLS Villavicencio… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Psidium guajava L.(Myrtaceae) leaves are used as an
herbal antidiabetic remedy in several parts of the world. On Madagascar, both the bark and …

A strategy for pinpointing natural bioactive components using two-dimensional bioassay profilings combined with comprehensive two-dimensional countercurrent …

P Xu, X Wang, T Lin, Q Shao, J Peng, C Chu… - Analytical …, 2022 - ACS Publications
Inspired by the interpretation of two-dimensional (2D) nuclear magnetic resonance spectra,
an efficient strategy was proposed for pinpointing bioactive components from complex …