Successful materials design for bone-tissue engineering requires an understanding of the
composition and structure of native bone tissue, as well as appropriate selection of …

Titanium (Ti) and its alloys have been widely used as orthopedic implants, because of their
favorable mechanical properties, corrosion resistance and biocompatibility. Despite their …

Proper immune responses are critical for successful biomaterial implantation. Here, four
scales of honeycomb-like TiO2 structures were custom made on titanium (Ti) substrates to …

Bone regeneration is a highly synchronized process that requires multiple biochemical,
bioelectrical, mechanical, and other physiological cues. The restoration and delivery of …

The development of new nanomaterials with high biomedical performance and low toxicity is
essential to obtain more efficient therapy and precise diagnostic tools and devices. Recently …

Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …

Osteomyelitis, as a severe bone disease caused by bacterial infection, can result in lifelong
disability or fatal sepsis. Considering that the infection is stubborn and deep-sited in bone …

Safe, effective, and convenient administration of therapeutic nanomaterials is one of the
greatest difficulties in nanomedicine. To tackle this challenge, a system which couples multi …

Macrophage polarization toward M1 phenotype (pro‐inflammation) is closely associated
with the destructive phase of periodontal inflammation. Nanoceria is verified to inhibit M1 …

An elevated bone microenvironmental reactive oxygen species (ROS) level is a hallmark of
osteoporosis that often leads to the dysfunction of bone-related mesenchymal stem cells …