Microneedle-based transdermal detection and sensing devices

J Wang, Z Lu, R Cai, H Zheng, J Yu, Y Zhang, Z Gu - Lab on a Chip, 2023 - pubs.rsc.org
Microneedles have been expected for the construction of next-generation biosensors
towards personalization, digitization, and intellectualization due to their metrics of minimal …

Disease detection with molecular biomarkers: from chemistry of body fluids to nature-inspired chemical sensors

YY Broza, X Zhou, M Yuan, D Qu, Y Zheng… - Chemical …, 2019 - ACS Publications
This article aims to review nature-inspired chemical sensors for enabling fast, relatively
inexpensive, and minimally (or non-) invasive diagnostics and follow-up of the health …

Continuous measurement of lactate concentration in human subjects through direct electron transfer from enzymes to microneedle electrodes

DME Freeman, DK Ming, R Wilson, PL Herzog… - ACS …, 2023 - ACS Publications
Microneedle lactate sensors may be used to continuously measure lactate concentration in
the interstitial fluid in a minimally invasive and pain-free manner. First-and second …

[HTML][HTML] Microneedle based electrochemical (Bio) Sensing: Towards decentralized and continuous health status monitoring

JJ García-Guzmán, C Pérez-Ràfols, M Cuartero… - TrAC Trends in …, 2021 - Elsevier
Microneedle (MN) based electrochemical (bio) sensing has become a growing field within
the discipline of analytical chemistry as a result of its unique capacity for continuous …

A neural probe for concurrent real-time measurement of multiple neurochemicals with electrophysiology in multiple brain regions in vivo

U Chae, J Woo, Y Cho, JK Han… - Proceedings of the …, 2023 - National Acad Sciences
Real-time monitoring of various neurochemicals with high spatial resolution in multiple brain
regions in vivo can elucidate neural circuits related to various brain diseases. However …

Coordinated acetylcholine release in prefrontal cortex and hippocampus is associated with arousal and reward on distinct timescales

LMTG Ruivo, KL Baker, MW Conway, PJ Kinsley… - Cell reports, 2017 - cell.com
Cholinergic neurotransmission throughout the neocortex and hippocampus regulates
arousal, learning, and attention. However, owing to the poorly characterized timing and …

Non-transdermal microneedles for advanced drug delivery

KJ Lee, MJ Goudie, P Tebon, W Sun, Z Luo… - Advanced drug delivery …, 2020 - Elsevier
Microneedles (MNs) have been used to deliver drugs for over two decades. These platforms
have been proven to increase transdermal drug delivery efficiency dramatically by …

Flexible fiber-based optoelectronics for neural interfaces

S Park, G Loke, Y Fink, P Anikeeva - Chemical Society Reviews, 2019 - pubs.rsc.org
Neurological and psychiatric conditions pose an increasing socioeconomic burden on our
aging society. Our ability to understand and treat these conditions relies on the development …

In vivo monitoring of oxygen in rat brain by carbon fiber microelectrode modified with antifouling nanoporous membrane

L Zhou, H Hou, H Wei, L Yao, L Sun, P Yu… - Analytical …, 2019 - ACS Publications
Oxygen (O2) is involved in many life activities, and its in vivo monitoring is of vital
importance. In vivo electrochemistry with carbon fiber microelectrode (CFME) has been …

Silk/polyols/GOD microneedle based electrochemical biosensor for continuous glucose monitoring

L Zhao, Z Wen, F Jiang, Z Zheng, S Lu - RSC advances, 2020 - pubs.rsc.org
This work illustrates the feasibility of a microneedle based electrochemical biosensor for
continuous glucose monitoring. The device consists of three silk/D-sorbitol pyramidal …