Calreticulin is an ER (endoplasmic reticulum) luminal Ca2+-buffering chaperone. The
protein is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity …

Apoptotic cell death is initiated by a morphologically homogenous entity that was considered
to be non-immunogenic and non-inflammatory in nature. However, recent advances suggest …

Ca2+ is a ubiquitous intracellular messenger responsible for controlling numerous cellular
processes including fertilization, mitosis, neuronal transmission, contraction and relaxation …

One of the obstacles to the potential clinical utility of bioengineered skeletal muscle is its
limited force generation capacity. Since engineered muscle, unlike most native muscle …

Integrins are heterodimeric, transmembrane receptors that are expressed in all cells,
including those in the heart. They participate in multiple critical cellular processes including …

The exposure of calreticulin (CRT) on the plasma membrane can precede anthracycline-
induced apoptosis and is required for cell death to be perceived as immunogenic. Mass …

Our previous study showed that Calreticulin (CRT) promoted the development of pancreatic
cancer (PC) through ERK/MAPK pathway. We next investigate whether CRT promotes EGF …

Calreticulin was first isolated 26 years ago. Since its discovery as a minor Ca 2+-binding
protein of the sarcoplasmic reticulum, the appreciation of its importance has grown, and it is …

Immunogenic apoptosis, or more appropriately called immunogenic cell death (ICD), is a
recently described form of apoptosis induced by a specific set of chemotherapeutic drugs or …

Muscle fibers attach to laminin in the basal lamina using two distinct mechanisms: the
dystrophin glycoprotein complex and the α7β1 integrin. Defects in these linkage systems …