[HTML][HTML] Endothelial dysfunction—a major mediator of diabetic vascular disease
The vascular endothelium is a multifunctional organ and is critically involved in modulating
vascular tone and structure. Endothelial cells produce a wide range of factors that also …
vascular tone and structure. Endothelial cells produce a wide range of factors that also …
[HTML][HTML] Metabolic syndrome, aging and involvement of oxidative stress
The prevalence of the metabolic syndrome, a cluster of cardiovascular risk factors
associated with obesity and insulin resistance, is dramatically increasing in Western and …
associated with obesity and insulin resistance, is dramatically increasing in Western and …
Endothelial dysfunction: clinical implications in cardiovascular disease and therapeutic approaches
KH Park, WJ Park - Journal of Korean medical science, 2015 - synapse.koreamed.org
Atherosclerosis is a chronic progressive vascular disease. It starts early in life, has a long
asymptomatic phase, and a progression accelerated by various cardiovascular risk factors …
asymptomatic phase, and a progression accelerated by various cardiovascular risk factors …
Oxidative stress in diabetes: implications for vascular and other complications
D Pitocco, M Tesauro, R Alessandro… - International journal of …, 2013 - mdpi.com
In recent decades, oxidative stress has become a focus of interest in most biomedical
disciplines and many types of clinical research. Increasing evidence shows that oxidative …
disciplines and many types of clinical research. Increasing evidence shows that oxidative …
Endothelial dysfunction in obesity
A Engin - Obesity and lipotoxicity, 2017 - Springer
Chronic inflammatory state in obesity causes dysregulation of the endocrine and paracrine
actions of adipocyte-derived factors, which disrupt vascular homeostasis and contribute to …
actions of adipocyte-derived factors, which disrupt vascular homeostasis and contribute to …
Endothelial dysfunction in obesity and therapeutic targets
A Engin - Obesity and Lipotoxicity, 2024 - Springer
Parallel to the increasing prevalence of obesity in the world, the mortality from
cardiovascular disease has also increased. Low-grade chronic inflammation in obesity …
cardiovascular disease has also increased. Low-grade chronic inflammation in obesity …
Obesity‐related metabolic syndrome: mechanisms of sympathetic overactivity
MP Canale, S Manca di Villahermosa… - International journal …, 2013 - Wiley Online Library
The prevalence of the metabolic syndrome has increased worldwide over the past few
years. Sympathetic nervous system overactivity is a key mechanism leading to hypertension …
years. Sympathetic nervous system overactivity is a key mechanism leading to hypertension …
Local peroxynitrite impairs endothelial transient receptor potential vanilloid 4 channels and elevates blood pressure in obesity
M Ottolini, K Hong, EL Cope, Z Daneva, LJ DeLalio… - Circulation, 2020 - Am Heart Assoc
Background: Impaired endothelium-dependent vasodilation is a hallmark of obesity-induced
hypertension. The recognition that Ca2+ signaling in endothelial cells promotes vasodilation …
hypertension. The recognition that Ca2+ signaling in endothelial cells promotes vasodilation …
The role of tissue renin-angiotensin-aldosterone system in the development of endothelial dysfunction and arterial stiffness
Epidemiological studies support the notion that arterial stiffness is an independent predictor
of adverse cardiovascular events contributing significantly to systolic hypertension, impaired …
of adverse cardiovascular events contributing significantly to systolic hypertension, impaired …
Endothelin-1 axes in the framework of predictive, preventive and personalised (3P) medicine
Abstract Endothelin-1 (ET-1) is involved in the regulation of a myriad of processes highly
relevant for physical and mental well-being; female and male health; in the modulation of …
relevant for physical and mental well-being; female and male health; in the modulation of …