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Advances and challenges in biotechnological production of chondroitin sulfate and its oligosaccharides
Chondroitin sulfate (CS) is a member of glycosaminoglycans (GAGs) and has critical
physiological functions. CS is widely applied in medical and clinical fields. Currently, the …
physiological functions. CS is widely applied in medical and clinical fields. Currently, the …
Advances in green bioproduction of marine and glycosaminoglycan oligosaccharides
C Deng, M Zhao, Q Zhao, L Zhao - Carbohydrate Polymers, 2023 - Elsevier
Functional oligosaccharides are a class of low-polymerization sugars with physiological
functions, showing great potential in the fields of food, medicine, and agriculture, with …
functions, showing great potential in the fields of food, medicine, and agriculture, with …
Biosynthesis of non-animal chondroitin sulfate from methanol using genetically engineered Pichia pastoris
Chondroitin sulfate (CS) is widely applied in the medical, clinical, and nutraceutical fields.
However, all commercialized CS is extracted from animal tissues, which is associated with …
However, all commercialized CS is extracted from animal tissues, which is associated with …
Enhancing the expression of chondroitin 4-O-sulfotransferase for one-pot enzymatic synthesis of chondroitin sulfate A
Chondroitin sulfate (CS) stands as a pivotal compound in dietary supplements for
osteoarthritis treatment, propelling significant interest in the biotechnological pursuit of …
osteoarthritis treatment, propelling significant interest in the biotechnological pursuit of …
Marine-derived uronic acid-containing polysaccharides: Structures, sources, production, and nutritional functions
Background Uronic acid-containing polysaccharides (UACPs) are a class of
polysaccharides containing at least one type of uronic acid (UA) and have been widely used …
polysaccharides containing at least one type of uronic acid (UA) and have been widely used …
Biosynthesis of non-sulfated high-molecular-weight glycosaminoglycans and specific-sized oligosaccharides
Non-sulfated forms of glycosaminoglycans (NSGAGs) including hyaluronan, chondroitin and
heparosan with high-molecular-weight (HMW) are extensively used biomaterials, while …
heparosan with high-molecular-weight (HMW) are extensively used biomaterials, while …
Microbial synthesis of glycosaminoglycans and their oligosaccharides
Compared with chemical synthesis and tissue extraction methods, microbial synthesis of
glycosaminoglycans (GAGs) is attractive because of the advantages of eco-friendly …
glycosaminoglycans (GAGs) is attractive because of the advantages of eco-friendly …
Microbial cell surface engineering for high-level synthesis of bio-products
Microbial cell surface layers, which mainly include the cell membrane, cell wall, periplasmic
space, outer membrane, capsules, S-layers, pili, and flagella, control material exchange …
space, outer membrane, capsules, S-layers, pili, and flagella, control material exchange …
Enzymatic production of chondroitin oligosaccharides and its sulfate derivatives
Chondroitin sulfate (CS) has a wide range of physiological functions and clinical
applications. However, the biosynthesis of chondroitin oligosaccharides (o-CHs) and sulfate …
applications. However, the biosynthesis of chondroitin oligosaccharides (o-CHs) and sulfate …
Optimizing the sulfation-modification system for scale preparation of chondroitin sulfate A
X **, Q Li, Y Wang, W Zhang, R Xu, J Li, G Du… - Carbohydrate …, 2020 - Elsevier
Chondroitin sulfate (CS) extracted from animal tissues has been widely used as
nutraceutical and pharmaceutical products for osteoarthritis treatment. Here we developed …
nutraceutical and pharmaceutical products for osteoarthritis treatment. Here we developed …