The history of colour is fascinating from a social and artistic viewpoint because it shows the
way; use; and importance acquired. The use of colours date back to the Stone Age (the first …

The use of biopharmaceuticals dates from the 19th century and within 5-10 years, up to 50%
of all drugs in development will be biopharmaceuticals. In the 1980s, the biopharmaceutical …

Background State-of-the-art strain engineering techniques for the host Pichia pastoris (syn.
Komagataella spp.) include overexpression of homologous and heterologous genes, and …

The methylotrophic yeast Pichia pastoris (syn. Komagataella spp.) is one of the most
important production systems for heterologous proteins. After the first genome sequences …

Over the past 100 years, industrial biotechnology has grown into a multibillion dollar market,
which now has even begun to include large parts of chemical, material, and fuel production …

Ever since agriculture started, plants have been bred to obtain better yields, better fruits, or
sustainable products under uncertain biotic and abiotic conditions. However, a new way to …

Recombinant protein subunit vaccines are formulated using defined protein antigens that
can be produced in heterologous expression systems. The methylotrophic yeast Pichia …

With nearly three decades of development, Pichia pastoris (P. pastoris) has become a
powerful eukaryotic protein expression system for the expression of thousands of proteins …

The transglutaminases form a large family of intracellular and extracellular enzymes that
catalyze cross-links between protein molecules. Transglutaminases crosslinking properties …

The industrial yeast Komagataella phaffii is a highly effective platform for heterologous
protein production, owing to its high protein expression and secretion capacity …