Testicular cancer is the most common malignancy among men between 14 and 44 years of
age, and its incidence has risen over the past two decades in Western countries. Both …

It is well established that human pluripotent stem cells (hPSCs) can acquire genetic and
epigenetic changes during culture in vitro. Given the increasing use of hPSCs in research …

Human pluripotent stem cells (PSCs) are a leading candidate for cell-based therapies
because of their capacity for unlimited self renewal and pluripotent differentiation. These …

The unique abilities of human pluripotent stem cells to self-renew and to differentiate into
cells of the three germ layers make them an invaluable tool for the future of regenerative …

We recently reported the development of TeSR1, a serum-free, animal product–free medium
that supports the derivation and long-term feeder-independent culture of human embryonic …

The application of human embryonic stem cells (HESCs) to provide differentiated cells for
regenerative medicine will require the continuous maintenance of the undifferentiated stem …

Human embryonic stem cells (HESCs) are the in vitro descendants of the pluripotent inner
cell mass (ICM) of human blastocyst stage embryos. HESCs can be kept undifferentiated in …

The amnion is the inner of two membranes surrounding the fetus. That it arises from
embryonic epiblast cells prior to gastrulation suggests that it may retain a reservoir of stem …

Studies using high-resolution genome-wide approaches have recently reported that
genomic and epigenomic alterations frequently accumulate in human pluripotent cells …

The mechanical properties of cells have been shown to be useful markers of cell state by the
biophysics community. Here, I highlight clinical and research problems that this label-free …