Ecologically mediated selection against hybrids, caused by hybrid phenotypes fitting poorly
into available niches, is typically viewed as distinct from selection caused by epistatic …

There is remarkable variation in the rate at which genetic incompatibilities in molecular
interactions accumulate. In some cases, minor changes—even single-nucleotide …

Mitochondrial (mt) and nuclear-encoded proteins are integrated in aerobic respiration,
requiring co-functionality among gene products from fundamentally different genomes …

Over the past 2 decades, biologists have come to appreciate that hybridization, or genetic
exchange between distinct lineages, is remarkably common—not just in particular lineages …

Genomic evidence supports an important role for selection in sha** patterns of
introgression along the genome, but frameworks for understanding the evolutionary …

The interaction and coevolution between nuclear and cytoplasmic genomes are one of the
fundamental hallmarks of eukaryotic genome evolution and, 2 billion yr later, are still major …

Background Mitochondrial genes and nuclear genes cooperate closely to maintain the
functions of mitochondria, especially in the oxidative phosphorylation (OXPHOS) pathway …