The gut microbiota have long been recognized to play a key role in human health and
disease. Currently, several lines of evidence from preclinical to clinical research have …

Neutrophils are crucial elements of innate immune system, which assure host defense via a
range of effector functions, such as phagocytosis, degranulation, and NET formation. The …

This is the first prospective study of the effects of human gut microbiota and metabolites on
immune checkpoint inhibitor (ICT) response in metastatic melanoma patients. Whereas …

The neutrophil is the major phagocyte and the final effector cell of the innate immunity, with a
primary role in the clearance of extracellular pathogens. Using the broad array of cytokines …

The past decade has witnessed groundbreaking advances in the field of microbiome
research. An area where immense implications of the microbiome have been demonstrated …

The intestinal microbiota has gained increased attention from researchers within the swine
industry due to its role in promoting intestinal maturation, immune system modulation, and …

Polyphenols are potent micronutrients that can be found in large quantities in various food
sources and spices. These compounds, also known as phenolics due to their phenolic …

Pharmacometabolomics (PMx) studies use information contained in metabolic profiles (or
metabolome) to inform about how a subject will respond to drug treatment. Genome, gut …

Staphylococcus aureus causes severe infections and among all methicillin-resistant S.
aureus (MRSA) remains a great challenge in spite of decade research of antibacterial …

Neutrophils undergo a unique form of cell death to generate neutrophil extracellular traps
(NETs). It is well established that citrullination of histones (eg, CitH3) facilitates chromatin …