The challenge of efflux-mediated antibiotic resistance in Gram-negative bacteria

XZ Li, P Plésiat, H Nikaido - Clinical microbiology reviews, 2015 - Am Soc Microbiol
The global emergence of multidrug-resistant Gram-negative bacteria is a growing threat to
antibiotic therapy. The chromosomally encoded drug efflux mechanisms that are ubiquitous …

Melioidosis

WJ Wiersinga, HS Virk, AG Torres, BJ Currie… - Nature reviews Disease …, 2018 - nature.com
Burkholderia pseudomallei is a Gram-negative environmental bacterium and the
aetiological agent of melioidosis, a life-threatening infection that is estimated to account …

Burkholderia pseudomallei and melioidosis

EM Meumann, D Limmathurotsakul… - Nature Reviews …, 2024 - nature.com
Burkholderia pseudomallei, the causative agent of melioidosis, is found in soil and water of
tropical and subtropical regions globally. Modelled estimates of the global burden predict …

[BOOK][B] Decolonizing extinction: The work of care in orangutan rehabilitation

JS Parreñas - 2018 - books.google.com
In Decolonizing Extinction Juno Salazar Parreñas ethnographically traces the ways in which
colonialism, decolonization, and indigeneity shape relations that form more-than-human …

Antibiotic resistance in Burkholderia species

KA Rhodes, HP Schweizer - Drug Resistance Updates, 2016 - Elsevier
The genus Burkholderia comprises metabolically diverse and adaptable Gram-negative
bacteria, which thrive in often adversarial environments. A few members of the genus are …

[HTML][HTML] Melioidosis diagnostic workshop, 2013

AR Hoffmaster, D AuCoin, P Baccam… - Emerging infectious …, 2015 - ncbi.nlm.nih.gov
Melioidosis is a severe disease that can be difficult to diagnose because of its diverse
clinical manifestations and a lack of adequate diagnostic capabilities for suspected cases …

Human melioidosis

I Gassiep, M Armstrong, R Norton - Clinical microbiology reviews, 2020 - Am Soc Microbiol
The causative agent of melioidosis, Burkholderia pseudomallei, a tier 1 select agent, is
endemic in Southeast Asia and northern Australia, with increased incidence associated with …

Melioidosis in Malaysia: incidence, clinical challenges, and advances in understanding pathogenesis

S Nathan, S Chieng, PV Kingsley, A Mohan… - Tropical medicine and …, 2018 - mdpi.com
Malaysia is an endemic hot spot for melioidosis; however, a comprehensive picture of the
burden of disease, clinical presentations, and challenges faced in diagnosis and treatment …

SPANDx: a genomics pipeline for comparative analysis of large haploid whole genome re-sequencing datasets

DS Sarovich, EP Price - BMC research notes, 2014 - Springer
Background Next-generation sequencing (NGS) is now a commonplace tool for molecular
characterisation of virtually any species of interest. Despite the ever-increasing use of NGS …

Antibiotic resistance markers in Burkholderia pseudomallei strain Bp1651 identified by genome sequence analysis

JV Bugrysheva, D Sue, JE Gee, MG Elrod… - Antimicrobial agents …, 2017 - Am Soc Microbiol
Burkholderia pseudomallei Bp1651 is resistant to several classes of antibiotics that are
usually effective for treatment of melioidosis, including tetracyclines, sulfonamides, and β …