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Identification of bioactive metabolites using activity metabolomics
The metabolome, the collection of small-molecule chemical entities involved in metabolism,
has traditionally been studied with the aim of identifying biomarkers in the diagnosis and …
has traditionally been studied with the aim of identifying biomarkers in the diagnosis and …
Statistical methods and resources for biomarker discovery using metabolomics
Metabolomics is a dynamic tool for elucidating biochemical changes in human health and
disease. Metabolic profiles provide a close insight into physiological states and are highly …
disease. Metabolic profiles provide a close insight into physiological states and are highly …
NOREVA: enhanced normalization and evaluation of time-course and multi-class metabolomic data
Biological processes (like microbial growth & physiological response) are usually dynamic
and require the monitoring of metabolic variation at different time-points. Moreover, there is …
and require the monitoring of metabolic variation at different time-points. Moreover, there is …
[HTML][HTML] California's forest carbon offsets buffer pool is severely undercapitalized
G Badgley, F Chay, OS Chegwidden… - Frontiers in Forests …, 2022 - frontiersin.org
California operates a large forest carbon offsets program that credits carbon stored in forests
across the continental United States and parts of coastal Alaska. These credits can be sold …
across the continental United States and parts of coastal Alaska. These credits can be sold …
The machine learning life cycle and the cloud: implications for drug discovery
Introduction: Artificial intelligence (AI) and machine learning (ML) are increasingly used in
many aspects of drug discovery. Larger data sizes and methods such as Deep Neural …
many aspects of drug discovery. Larger data sizes and methods such as Deep Neural …
Unraveling the role of cloud computing in health care system and biomedical sciences
Cloud computing has emerged as a transformative force in healthcare and biomedical
sciences, offering scalable, on-demand resources for managing vast amounts of data. This …
sciences, offering scalable, on-demand resources for managing vast amounts of data. This …
DeepCell Kiosk: scaling deep learning–enabled cellular image analysis with Kubernetes
Deep learning is transforming the analysis of biological images, but applying these models
to large datasets remains challenging. Here we describe the DeepCell Kiosk, cloud-native …
to large datasets remains challenging. Here we describe the DeepCell Kiosk, cloud-native …
[HTML][HTML] MassGenie: a transformer-based deep learning method for identifying small molecules from their mass spectra
The 'inverse problem'of mass spectrometric molecular identification ('given a mass spectrum,
calculate/predict the 2D structure of the molecule whence it came') is largely unsolved, and …
calculate/predict the 2D structure of the molecule whence it came') is largely unsolved, and …
NMR: unique strengths that enhance modern metabolomics research
Nuclear magnetic resonance (NMR) spectroscopy is an important analytical technique in
metabolomics. Because it provides atomic-level detail of small molecules, NMR is …
metabolomics. Because it provides atomic-level detail of small molecules, NMR is …
[HTML][HTML] Towards a comprehensive characterisation of the human internal chemical exposome: Challenges and perspectives
The holistic characterisation of the human internal chemical exposome using high-resolution
mass spectrometry (HRMS) would be a step forward to investigate the environmental …
mass spectrometry (HRMS) would be a step forward to investigate the environmental …