A unifying perspective on neural manifolds and circuits for cognition

C Langdon, M Genkin, TA Engel - Nature Reviews Neuroscience, 2023 - nature.com
Two different perspectives have informed efforts to explain the link between the brain and
behaviour. One approach seeks to identify neural circuit elements that carry out specific …

Cortical hierarchy, dual counterstream architecture and the importance of top-down generative networks

J Vezoli, L Magrou, R Goebel, XJ Wang, K Knoblauch… - Neuroimage, 2021 - Elsevier
Hierarchy is a major organizational principle of the cortex and underscores modern
computational theories of cortical function. The local microcircuit amplifies long-distance …

Computing by robust transience: how the fronto-parietal network performs sequential, category-based decisions

W Chaisangmongkon, SK Swaminathan, DJ Freedman… - Neuron, 2017 - cell.com
Decision making involves dynamic interplay between internal judgements and external
perception, which has been investigated in delayed match-to-category (DMC) experiments …

Modelling human behaviour in cognitive tasks with latent dynamical systems

PI Jaffe, RA Poldrack, RJ Schafer… - Nature Human Behaviour, 2023 - nature.com
Response time data collected from cognitive tasks are a cornerstone of psychology and
neuroscience research, yet existing models of these data either make strong assumptions …

Map** of functionally characterized cell classes onto canonical circuit operations in primate prefrontal cortex

S Ardid, M Vinck, D Ka**, S Marquez… - Journal of …, 2015 - Soc Neuroscience
Microcircuits are composed of multiple cell classes that likely serve unique circuit
operations. But how cell classes map onto circuit functions is largely unknown, particularly …

Latent circuit inference from heterogeneous neural responses during cognitive tasks

C Langdon, TA Engel - Nature Neuroscience, 2025 - nature.com
Higher cortical areas carry a wide range of sensory, cognitive and motor signals mixed in
heterogeneous responses of single neurons tuned to multiple task variables. Dimensionality …

Inferring context-dependent computations through linear approximations of prefrontal cortex dynamics

J Soldado-Magraner, V Mante, M Sahani - Science Advances, 2024 - science.org
The complex neural activity of prefrontal cortex (PFC) is a hallmark of cognitive processes.
How these rich dynamics emerge and support neural computations is largely unknown …

The controllosphere: The neural origin of cognitive effort.

CB Holroyd - Psychological Review, 2024 - psycnet.apa.org
Why do some mental activities feel harder than others? The answer to this question is
surprisingly controversial. Current theories propose that cognitive effort affords a …

Tonic exploration governs both flexibility and lapses

RB Ebitz, BJ Sleezer, HP Jedema… - PLoS computational …, 2019 - journals.plos.org
In many cognitive tasks, lapses (spontaneous errors) are tacitly dismissed as the result of
nuisance processes like sensorimotor noise, fatigue, or disengagement. However, some …

Stochastic dynamics underlying cognitive stability and flexibility

K Ueltzhöffer, DJN Armbruster-Genç… - PLoS computational …, 2015 - journals.plos.org
Cognitive stability and flexibility are core functions in the successful pursuit of behavioral
goals. While there is evidence for a common frontoparietal network underlying both …