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An updated review on synthetic cathinones
Cathinone, the main psychoactive compound found in the plant Catha edulis Forsk.(khat), is
a β-keto analogue of amphetamine, sharing not only the phenethylamine structure, but also …
a β-keto analogue of amphetamine, sharing not only the phenethylamine structure, but also …
Abuse potential and toxicity of the synthetic cathinones (ie,“Bath salts”)
AL Riley, KH Nelson, P To, R López-Arnau, P Xu… - Neuroscience & …, 2020 - Elsevier
The synthetic cathinones are derived from the naturally occurring drug cathinone found in
the khat plant (Catha edulis) and have chemical structures and neurochemical …
the khat plant (Catha edulis) and have chemical structures and neurochemical …
[HTML][HTML] Molecular and clinical aspects of potential neurotoxicity induced by new psychoactive stimulants and psychedelics
New psychoactive stimulants and psychedelics continue to play an important role on the
illicit new psychoactive substance (NPS) market. Designer stimulants and psychedelics both …
illicit new psychoactive substance (NPS) market. Designer stimulants and psychedelics both …
Psychoactive drugs—from chemical structure to oxidative stress related to dopaminergic neurotransmission. A review
Nowadays, more and more young people want to experience illegal, psychoactive
substances, without knowing the risks of exposure. Besides affecting social life …
substances, without knowing the risks of exposure. Besides affecting social life …
Neurotoxicology of synthetic cathinone analogs
M Angoa-Pérez, JH Anneken, DM Kuhn - Neuropharmacology of New …, 2017 - Springer
The present review briefly explores the neurotoxic properties of methcathinone,
mephedrone, methylone, and methylenedioxypyrovalerone (MDPV), four synthetic …
mephedrone, methylone, and methylenedioxypyrovalerone (MDPV), four synthetic …
3, 4-Methylenedioxypyrovalerone (MDPV): in vitro mechanisms of hepatotoxicity under normothermic and hyperthermic conditions
Synthetic cathinones have emerged in recreational drug markets as legal alternatives for
classical amphetamines. Though currently banned in several countries, 3, 4 …
classical amphetamines. Though currently banned in several countries, 3, 4 …
Editor's Highlight: characterization of hepatotoxicity mechanisms triggered by designer cathinone drugs (β-Keto Amphetamines)
The use of cathinone designer drugs in recreational settings has been associated with
severe toxic effects, including liver damage. The precise mechanisms by which cathinones …
severe toxic effects, including liver damage. The precise mechanisms by which cathinones …
Structure-cytotoxicity relationship profile of 13 synthetic cathinones in differentiated human SH-SY5Y neuronal cells
Synthetic cathinones also known as β-keto amphetamines are a new group of recreational
designer drugs. We aimed to evaluate the cytotoxic potential of thirteen cathinones lacking …
designer drugs. We aimed to evaluate the cytotoxic potential of thirteen cathinones lacking …
Effects of mephedrone and amphetamine exposure during adolescence on spatial memory in adulthood: Behavioral and neurochemical analysis
P Grochecki, I Smaga, M Lopatynska-Mazurek… - International Journal of …, 2021 - mdpi.com
A synthetic cathinone, mephedrone is widely abused by adolescents and young adults.
Despite its widespread use, little is known regarding its long-term effects on cognitive …
Despite its widespread use, little is known regarding its long-term effects on cognitive …
[HTML][HTML] Binge-like mephedrone treatment induces memory impairment concomitant with brain kynurenic acid reduction in mice
M Marszalek-Grabska, I Zakrocka, B Budzynska… - Toxicology and Applied …, 2022 - Elsevier
Abstract While mephedrone (4-methylmethcathinone), a synthetic cathinone derivative, is
widely abused by adolescents and young adults, the knowledge about its long-term effects …
widely abused by adolescents and young adults, the knowledge about its long-term effects …