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[HTML][HTML] Imidazoles as potential anticancer agents: An update on recent studies
Nitrogen-containing heterocyclic rings are common structural components of marketed
drugs. Among these heterocycles, imidazole/fused imidazole rings are present in a wide …
drugs. Among these heterocycles, imidazole/fused imidazole rings are present in a wide …
Recent advances in the transition-metal-free synthesis of quinoxalines
Quinoxalines, also known as benzo [a] pyrazines, constitute an important class of nitrogen-
containing heterocyclic compounds as a result of their widespread prevalence in natural …
containing heterocyclic compounds as a result of their widespread prevalence in natural …
Synthesis, non-covalent interactions and chemical reactivity of 1-pentyl-3-phenylquinoxalin-2 (1H)-one—Structural and computational studies
This contribution presents the synthesis of a new quinoxaline derivative, 1-pentyl-3-
phenylquinoxalin-2 (1H)-one with formula C 19 H 20 N 2 O, through an alkylation reaction …
phenylquinoxalin-2 (1H)-one with formula C 19 H 20 N 2 O, through an alkylation reaction …
Recent advances on quinoxalines as target‐oriented chemotherapeutic anticancer agents through apoptosis
The current review outlines all possible recent synthetic platforms to quinoxaline derivatives
and the potent stimulated apoptosis mechanisms targeted by anticancer therapies. The …
and the potent stimulated apoptosis mechanisms targeted by anticancer therapies. The …
Medicinal Chemistry Perspectives on Recent Advances in Src Kinase Inhibitors as a Potential Target for the Development of Anticancer Agents: Biological Profile …
The physiological Src proto‐oncogene is a protein tyrosine kinase receptor that served as
the essential signaling pathway in different types of cancer. Src kinase receptor is divided …
the essential signaling pathway in different types of cancer. Src kinase receptor is divided …
Novel penta-1, 4-diene-3-one derivatives containing quinazoline and oxime ether fragments: Design, synthesis and bioactivity
S Su, M Chen, Q Li, Y Wang, S Chen, N Sun… - Bioorganic & Medicinal …, 2021 - Elsevier
A series of novel penta-1, 4-diene-3-one derivatives containing quinazoline and oxime ether
moieties were designed and synthesized. Their anticancer activities were evaluated by MTT …
moieties were designed and synthesized. Their anticancer activities were evaluated by MTT …
Recent updates on the anticancer activity of quinoxaline hybrids (Jan. 2017-Jan. 2022)
LS Feng, C Gao, FW Liu, XP Wang… - Current topics in …, 2022 - benthamdirect.com
Cancer being one of the leading causes of death among non-communicable diseases, has
already posed a heavy burden on the world health system. Chemotherapy is one of the most …
already posed a heavy burden on the world health system. Chemotherapy is one of the most …
Recent advances in the development of nitrogencontaining heterocyclic compounds as anticancer agents: a review
N-heterocyclic compounds are a natural and rich source of pharmacologically active
molecules displaying anti-cancer properties through various antiproliferative mechanisms …
molecules displaying anti-cancer properties through various antiproliferative mechanisms …
Imidazoquinoxaline as a privileged fused pharmacophore in anticancer drug development: a review of synthetic strategies and medicinal aspects
Cancer, the uncontrolled growth of cells, is not a single but a multifaceted disorder with
malignant behavior, metastasis, and invasion, medically known as malignant neoplasm. The …
malignant behavior, metastasis, and invasion, medically known as malignant neoplasm. The …
Discovery of 1, 4-pentadien-3-one derivatives containing quinoxaline scaffolds as potential apoptosis inducers
Aim: To synthesize novel antiproliferative agents. Results & methodology: A variety of 1, 4-
pentadien-3-one derivatives bearing quinoxaline scaffolds was designed and synthesized …
pentadien-3-one derivatives bearing quinoxaline scaffolds was designed and synthesized …