Alginate hydrogels are extremely versatile and adaptable biomaterials, with great potential
for use in biomedical applications. Their extracellular matrix-like features have been key …

Efforts to develop novel cell-based therapies originated with the first bone marrow transplant
on a leukemia patient in 1956. Preclinical and clinical examples of cell-based treatment …

The number of clinical trials using mesenchymal stem cells (MSCs) has increased since
2008, but this trend slowed in the past several years and dropped precipitously in 2018 …

Stem cell transplantation has been recognized as a promising strategy to induce the
regeneration of injured and diseased tissues and sustain therapeutic molecules for …

Background Stem cells for cardiac repair have shown promise in preclinical trials, but lower
than expected retention, viability, and efficacy. Encapsulation is one potential strategy to …

Mesenchymal stromal/stem cells (MSCs) have been investigated extensively through the
past years, proving to have great clinical therapeutic potential. In vitro cultivation of MSCs in …

Stem cell therapies have emerged as promising treatments for injuries and diseases in
regenerative medicine. Yet, delivering stem cells therapeutically can be complicated by …

Mesenchymal stem cells (MSC) hold promise in promoting vascular regeneration of
ischemic tissue in conditions like critical limb ischemia of the leg. However, this approach …

Bone marrow derived mesenchymal stem cells (MSCs) are regularly utilized for translational
therapeutic strategies including cell therapy, tissue engineering, and regenerative medicine …

Background During myocardial ischemia/reperfusion (MI/R) injury, there is extensive release
of immunogenic metabolites that activate cells of the innate immune system. These include …