Exploring the relationship between anastasis and mitochondrial ROS-mediated ferroptosis in metastatic chemoresistant cancers: a call for investigation

Y Cao, C Lu, NM Beeraka, S Efetov, M Enikeev… - Frontiers in …, 2024 - frontiersin.org
Ferroptosis induces significant changes in mitochondrial morphology, including membrane
condensation, volume reduction, cristae alteration, and outer membrane rupture, affecting …

Neuroprotective potential of flavonoids in brain disorders

S Hasan, N Khatri, ZN Rahman, AA Menezes, J Martini… - Brain Sciences, 2023 - mdpi.com
Flavonoids are a large subgroup of polyphenols known to be sourced from over 6000
natural products, including fruits, vegetables, bark, and herbs. Due to their antioxidant …

Green-synthesized silver nanoparticles from peel extract of pumpkin as a potent radiosensitizer against triple-negative breast cancer (TNBC)

S Montazersaheb, A Eftekhari, A Shafaroodi… - Cancer …, 2024 - Springer
Background Triple-negative breast cancer (TNBC) is an aggressive subtype of breast
cancer. Radiation therapy (RT) is a modality for TNBC management. Radiosensitizers can …

Preparation, optimization and in-vitro evaluation of curcumin-loaded niosome@ calcium alginate nanocarrier as a new approach for breast cancer treatment

I Akbarzadeh, M Shayan, M Bourbour, M Moghtaderi… - Biology, 2021 - mdpi.com
Simple Summary We provided an effective approach for the treatment of breast cancer as a
malignant disease. Regards to this, we used drug delivery system. This approach does not …

Controlled intracellular polymerization for cancer treatment

Y Zhang, Q Gao, W Li, R He, L Zhu, Q Lian, L Wang… - JACS Au, 2022 - ACS Publications
Numerous prodrugs have been developed and used for cancer treatments to reduce side
effects and promote efficacy. In this work, we have developed a new photoactivatable …

Single-cell omics traces the heterogeneity of prostate cancer cells and the tumor microenvironment

X Yu, R Liu, W Gao, X Wang, Y Zhang - Cellular & Molecular Biology …, 2023 - Springer
Prostate cancer is one of the more heterogeneous tumour types. In recent years, with the
rapid development of single-cell sequencing and spatial transcriptome technologies …

Fabricating niosomal-PEG nanoparticles co-loaded with metformin and silibinin for effective treatment of human lung cancer cells

E Salmani-Javan, D Jafari-Gharabaghlou… - Frontiers in …, 2023 - frontiersin.org
Background Despite current therapies, lung cancer remains a global issue and requires the
creation of novel treatment methods. Recent research has shown that biguanides such as …

The Prognosis of Cancer Depends on the Interplay of Autophagy, Apoptosis, and Anoikis within the Tumor Microenvironment

S Gulia, P Chandra, A Das - Cell Biochemistry and Biophysics, 2023 - Springer
Within the tumor microenvironment, the fight between the immune system and cancer
influences tumor transformation. Metastasis formation is an important stage in the …

[HTML][HTML] Marine-derived antimicrobial peptide piscidin-1 triggers extrinsic and intrinsic apoptosis in oral squamous cell carcinoma through reactive oxygen species …

FC Chiu, HM Kuo, CL Yu, P Selvam, IL Su… - Free Radical Biology …, 2024 - Elsevier
Cancer of the head and neck encompasses a wide range of cancers, including oral and
oropharyngeal cancers. Oral cancer is often diagnosed at advanced stages and has a …

Morpholine substituted quinazoline derivatives as anticancer agents against MCF-7, A549 and SHSY-5Y cancer cell lines and mechanistic studies

AR Dwivedi, V Kumar, V Prashar, A Verma… - RSC Medicinal …, 2022 - pubs.rsc.org
A series of morpholine substituted quinazoline derivatives have been synthesized and
evaluated for cytotoxic potential against A549, MCF-7 and SHSY-5Y cancer cell lines. These …