[HTML][HTML] Excess body weight: Novel insights into its roles in obesity comorbidities
Excess body weight is a global health problem due to sedentary lifestyle and unhealthy diet,
affecting 2 billion population worldwide. Obesity is a major risk factor for metabolic diseases …
affecting 2 billion population worldwide. Obesity is a major risk factor for metabolic diseases …
Caloric restriction in humans: impact on physiological, psychological, and behavioral outcomes
LM Redman, E Ravussin - 2010 - liebertpub.com
The current societal environment is marked by overabundant accessibility of food coupled
with a strong trend of reduced physical activity, both leading to the development of a …
with a strong trend of reduced physical activity, both leading to the development of a …
Treatment of diabetes in older adults: an Endocrine Society clinical practice guideline
D LeRoith, GJ Biessels, SS Braithwaite… - The Journal of …, 2019 - academic.oup.com
Objective The objective is to formulate clinical practice guidelines for the treatment of
diabetes in older adults. Conclusions Diabetes, particularly type 2, is becoming more …
diabetes in older adults. Conclusions Diabetes, particularly type 2, is becoming more …
Depot-specific differences and insufficient subcutaneous adipose tissue angiogenesis in human obesity
O Gealekman, N Guseva, C Hartigan, S Apotheker… - Circulation, 2011 - Am Heart Assoc
Background—Adipose tissue expands in response to excess caloric intake, but individuals
prone to deposit visceral instead of subcutaneous adipose tissue have higher risk of …
prone to deposit visceral instead of subcutaneous adipose tissue have higher risk of …
Effect of calorie restriction with or without exercise on insulin sensitivity, β-cell function, fat cell size, and ectopic lipid in overweight subjects
OBJECTIVE—The purpose of this article was to determine the relationships among total
body fat, visceral adipose tissue (VAT), fat cell size (FCS), ectopic fat deposition in liver …
body fat, visceral adipose tissue (VAT), fat cell size (FCS), ectopic fat deposition in liver …
Pancreatic fat content and β-cell function in men with and without type 2 diabetes
ME Tushuizen, MC Bunck, PJ Pouwels… - Diabetes …, 2007 - Am Diabetes Assoc
OBJECTIVE—Insulin resistance, associated with increased lipolysis, results in a high
exposure of nonadipose tissue to lipids. Experimental data indicate that fatty infiltration of …
exposure of nonadipose tissue to lipids. Experimental data indicate that fatty infiltration of …
Pancreatic fat is negatively associated with insulin secretion in individuals with impaired fasting glucose and/or impaired glucose tolerance: a nuclear magnetic …
Background The pathogenesis of type 2 diabetes is characterized by insulin resistance and
β‐cell dysfunction. Pancreatic fat load may add to the development of β‐cell dysfunction …
β‐cell dysfunction. Pancreatic fat load may add to the development of β‐cell dysfunction …
Effects of age and sex on postprandial glucose metabolism: differences in glucose turnover, insulin secretion, insulin action, and hepatic insulin extraction
R Basu, C Dalla Man, M Campioni, A Basu, G Klee… - Diabetes, 2006 - Am Diabetes Assoc
To determine the effects of age and sex on the regulation of postprandial glucose
metabolism, glucose turnover, insulin secretion, insulin action, and hepatic insulin extraction …
metabolism, glucose turnover, insulin secretion, insulin action, and hepatic insulin extraction …
Assessment of β-cell function in humans, simultaneously with insulin sensitivity and hepatic extraction, from intravenous and oral glucose tests
Assessment of insulin secretion in humans under physiological conditions has been a
challenge because of its complex interplay with insulin action and hepatic insulin extraction …
challenge because of its complex interplay with insulin action and hepatic insulin extraction …
Associations of abdominal subcutaneous and visceral fat with insulin resistance and secretion differ between men and women: the Netherlands epidemiology of …
Background: Abdominal obesity is a well-established risk factor for the development of type
2 diabetes. However, sex differences may exist. We aimed to investigate the associations of …
2 diabetes. However, sex differences may exist. We aimed to investigate the associations of …