A complex balanced equilibrium of the bacterial ecosystems exists in the oral cavity that can
be altered by tobacco smoking, psychological stressors, bad dietary habit, and chronic …

Microbial species colonizing host ecosystems in health or disease rarely do so alone.
Organisms conglomerate into dynamic heterotypic communities or biofilms in which …

Objectives Dental caries is a result of the ecological dysfunction of the polymicrobial
community on the tooth surface, which evolves through microbial interactions. In this study …

INTRODUCTION Periodontal bacteria can infiltrate the epithelium, activate signaling
pathways, induce inflammation, and block natural killer and cytotoxic cells, all of which …

Simple Summary Microbial dysbiosis has been credited as one of the contributing factors to
the development and progression of gastrointestinal tract cancer. The altered microbiota …

Periodontal microbiology has historically been based on an “us against them” paradigm,
one that focuses mainly on identifying microbes and viruses that cause disease. However …

In contrast to mammalian cells, bacterial cells lack mRNA polyadenylated tails, presenting a
hurdle in isolating mRNA amidst the prevalent rRNA during single-cell RNA-seq. This study …

Streptococcus mutans and Candida albicans exhibit strong cariogenicity through cross-
kingdom biofilm formation during the pathogenesis of dental caries. Caffeic acid phenethyl …

Aim Coaggregation, a highly specific cell–cell interaction mechanism, plays a pivotal role in
multispecies biofilm formation. While it has been mostly studied in oral environments, its …

The onset and development of periodontitis centers around microbiota dysbiosis and
disrupted host responses. Dynamic metabolic activities of the subgingival microbiota modify …