Evolutionary pathways and trajectories in antibiotic resistance
Evolution is the hallmark of life. Descriptions of the evolution of microorganisms have
provided a wealth of information, but knowledge regarding “what happened” has precluded …
provided a wealth of information, but knowledge regarding “what happened” has precluded …
Regulatory mechanisms of the LuxS/AI-2 system and bacterial resistance
Y Wang, B Liu, D Grenier, L Yi - Antimicrobial agents and …, 2019 - Am Soc Microbiol
The quorum-sensing (QS) system is an intercellular cell-cell communication mechanism that
controls the expression of genes involved in a variety of cellular processes and that plays …
controls the expression of genes involved in a variety of cellular processes and that plays …
Cooperative antibiotic resistance facilitates horizontal gene transfer
The rise of β-lactam resistance among pathogenic bacteria, due to the horizontal transfer of
plasmid-encoded β-lactamases, is a current global health crisis. Importantly, β-lactam …
plasmid-encoded β-lactamases, is a current global health crisis. Importantly, β-lactam …
[HTML][HTML] Interactions between plasmids and other mobile genetic elements affect their transmission and persistence
Plasmids are genetic elements that play a role in bacterial evolution by providing new genes
that promote adaptation to diverse conditions. Plasmids are also known to reduce bacterial …
that promote adaptation to diverse conditions. Plasmids are also known to reduce bacterial …
Metagenomic investigation of antibiotic resistance genes and resistant bacteria contamination in pharmaceutical plant sites in China
Pharmaceutical plant sites play a significant role in the dissemination of antibiotic resistance
genes (ARGs) into the environment. It is imperative to comprehensively monitor of ARGs …
genes (ARGs) into the environment. It is imperative to comprehensively monitor of ARGs …
A mathematician's guide to plasmids: an introduction to plasmid biology for modellers
Plasmids, extrachromosomal DNA molecules commonly found in bacterial and archaeal
cells, play an important role in bacterial genetics and evolution. Our understanding of …
cells, play an important role in bacterial genetics and evolution. Our understanding of …
Towards a better understanding of antimicrobial resistance dissemination: what can be learnt from studying model conjugative plasmids?
Bacteria can evolve rapidly by acquiring new traits such as virulence, metabolic properties,
and most importantly, antimicrobial resistance, through horizontal gene transfer (HGT) …
and most importantly, antimicrobial resistance, through horizontal gene transfer (HGT) …
Fitness cost of a mcr-1-carrying IncHI2 plasmid
K Ma, Y Feng, Z Zong - PLoS One, 2018 - journals.plos.org
IncHI2 is a common type of large mcr-1-carrying plasmids that have been found worldwide.
Large plasmids could impose metabolic burden for host bacterial strains, we therefore …
Large plasmids could impose metabolic burden for host bacterial strains, we therefore …
[HTML][HTML] Multiple driving factors contribute to the variations of typical antibiotic resistance genes in different parts of soil-lettuce system
X Wen, J Xu, G **ang, Z Cao, Q Yan, J Mi, B Ma… - Ecotoxicology and …, 2021 - Elsevier
The application of manure compost may cause the transmission of antibiotic resistance
genes (ARGs) in agroecological environment, which poses a global threat to public health …
genes (ARGs) in agroecological environment, which poses a global threat to public health …
Genomics, transcriptomics, and metabolomics reveal that minimal modifications in the host are crucial for the compensatory evolution of ColE1-like plasmids
Plasmid-mediated antimicrobial resistance is one of the major threats to public health
worldwide. The mechanisms involved in the plasmid/host coadaptation are still poorly …
worldwide. The mechanisms involved in the plasmid/host coadaptation are still poorly …