Abstract Bisphenol A (BPA; 4, 4′-isopropylidenediphenol) is an endocrine disruptor that is
used as a material for the production of phenol resins, polyacrylates, polyesters, epoxy …

The blood-brain barrier (BBB) is a highly specialized brain endothelial structure of the fully
differentiated neurovascular system. In concert with pericytes, astrocytes, and microglia, the …

The pathology of Alzheimer's disease (AD) is highly correlated with obesity-induced insulin
resistance. Resveratrol (Res) is a natural phenol that demonstrates a neuroprotective effect …

Glucose is the obligate energetic fuel for the mammalian brain, and most studies of cerebral
energy metabolism assume that the majority of cerebral glucose utilization fuels neuronal …

Neurons need a continuous supply of glucose, the major source of energy for mammalian
brain metabolism. The central nervous system is protected by three main physiological cell …

We previously demonstrated that mitochondrial bioenergetic deficits in the female brain
accompanied reproductive senescence and was accompanied by a shift from an aerobic …

Astrocytes play a critical role in regulation of extracellular neurotransmitter levels in the
central nervous system. This function is particularly prominent for the excitatory amino acid …

We present and discuss the role of endothelial and astroglial cells in managing the blood-
brain barrier (BBB) and aspects of pathological alterations in the BBB. The impact of …

Brain glucose uptake/metabolism is impaired in Alzheimer disease (AD). Here, we report
that levels of the two major brain glucose transporters (GLUT1 and GLUT3) responsible for …

Cerebral glucose homeostasis deregulation has a role in the pathogenesis and the
progression of Alzheimer's disease (AD). Current therapies delay symptoms without …