Commonly consumed foods and beverages can contain chemicals with reported
carcinogenic activity in rodent models. Moreover, exposures to some of these substances …

Objectives This report reviews the carcinogenicity of multi‐walled carbon nanotubes
(MWCNTs) in experimental animals, concentrating on MWNT‐7, a straight fibrous MWCNT …

In the deliberations over many years on the question of thresholds for the carcinogenicity of
chemicals, the dominant paradigm has been the linear no-threshold (LNT) model, derived …

Dioxane is a widely used synthetic industrial chemical and its contamination of drinking
water and food is a potential health concern. It induces liver tumors when administered in …

Chemicals with carcinogenic activity in either animals or humans produce increases in
neoplasia through diverse mechanisms. One mechanism is reaction with nuclear DNA …

Exposure to acrylonitrile induces formation of tumors at multiple sites in rats, with females
being more sensitive. The present study assessed possible mechanisms of acrylonitrile …

For genotoxic carcinogens, covalent binding to DNA is a critical initiating event in
tumorigenesis. The present research investigated dose-effect relationships of three …

Genotoxic carcinogens are regulated under the policy that there is no threshold or safe
dose. It has been pointed out, however, that self‐defense mechanisms, such as …