Ventilator-associated pneumonia in adults: a narrative review

L Papazian, M Klompas, CE Luyt - Intensive care medicine, 2020 - Springer
Ventilator-associated pneumonia (VAP) is one of the most frequent ICU-acquired infections.
Reported incidences vary widely from 5 to 40% depending on the setting and diagnostic …

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia

Q Zhang, C Li, HV Worthington… - Cochrane Database of …, 2020 - cochranelibrary.com
Background Ventilator‐associated pneumonia (VAP) is defined as pneumonia develo** in
people who have received mechanical ventilation for at least 48 hours. VAP is a potentially …

International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia: Guidelines for the …

A Torres, MS Niederman, J Chastre… - European …, 2017 - Eur Respiratory Soc
The most recent European guidelines and task force reports on hospital-acquired
pneumonia (HAP) and ventilator-associated pneumonia (VAP) were published almost 10 …

Strategies to prevent ventilator-associated pneumonia, ventilator-associated events, and nonventilator hospital-acquired pneumonia in acute-care hospitals: 2022 …

M Klompas, R Branson, K Cawcutt, M Crist… - Infection Control & …, 2022 - cambridge.org
The purpose of this document is to highlight practical recommendations to assist acute care
hospitals to prioritize and implement strategies to prevent ventilator-associated pneumonia …

Strategies to prevent ventilator-associated pneumonia in acute care hospitals: 2014 update

M Klompas, R Branson, EC Eichenwald… - Infection Control & …, 2014 - cambridge.org
Previously published guidelines are available that provide comprehensive
recommendations for detecting and preventing healthcare-associated infections (HAIs). The …

Pseudomonas aeruginosa Biofilms: Host Response and Clinical Implications in Lung Infections

NM Maurice, B Bedi, RT Sadikot - American journal of respiratory …, 2018 - atsjournals.org
Pseudomonas aeruginosa is a major health challenge that causes recalcitrant multidrug-
resistant infections, especially in immunocompromised and hospitalized patients. P …

Update of the treatment of nosocomial pneumonia in the ICU

R Zaragoza, P Vidal-Cortés, G Aguilar, M Borges… - Critical Care, 2020 - Springer
In accordance with the recommendations of, amongst others, the Surviving Sepsis
Campaign and the recently published European treatment guidelines for hospital-acquired …

Epidemiology and microbiology of ventilator-associated pneumonia in COVID-19 patients: a multicenter retrospective study in 188 patients in an un-inundated French …

G Blonz, A Kouatchet, N Chudeau, E Pontis, J Lorber… - Critical care, 2021 - Springer
Background The COVID-19 pandemic is responsible for many hospitalizations in intensive
care units (ICU), with widespread use of invasive mechanical ventilation (IMV) which …

Diagnosis of ventilator-associated pneumonia in critically ill adult patients—a systematic review and meta-analysis

SM Fernando, A Tran, W Cheng, M Klompas… - Intensive care …, 2020 - Springer
The accuracy of the signs and tests that clinicians use to diagnose ventilator-associated
pneumonia (VAP) and initiate antibiotic treatment has not been well characterized. We …

Alveolar macrophages are epigenetically altered after inflammation, leading to long-term lung immunoparalysis

A Roquilly, C Jacqueline, M Davieau, A Mollé… - Nature …, 2020 - nature.com
Sepsis and trauma cause inflammation and elevated susceptibility to hospital-acquired
pneumonia. As phagocytosis by macrophages plays a critical role in the control of bacteria …