Collagen-and hyaluronic acid-based hydrogels and their biomedical applications
Hydrogels have been widely investigated in biomedical fields due to their similar physical
and biochemical properties to the extracellular matrix (ECM). Collagen and hyaluronic acid …
and biochemical properties to the extracellular matrix (ECM). Collagen and hyaluronic acid …
Extracellular matrix assembly: a multiscale deconstruction
The biochemical and biophysical properties of the extracellular matrix (ECM) dictate tissue-
specific cell behaviour. The molecules that are associated with the ECM of each tissue …
specific cell behaviour. The molecules that are associated with the ECM of each tissue …
Fractal-like hierarchical organization of bone begins at the nanoscale
INTRODUCTION The components of bone assemble hierarchically to provide stiffness and
toughness. Deciphering the specific organization and relationship between bone's principal …
toughness. Deciphering the specific organization and relationship between bone's principal …
Collagen structure and stability
MD Shoulders, RT Raines - Annual review of biochemistry, 2009 - annualreviews.org
Collagen is the most abundant protein in animals. This fibrous, structural protein comprises
a right-handed bundle of three parallel, left-handed polyproline II-type helices. Much …
a right-handed bundle of three parallel, left-handed polyproline II-type helices. Much …
Microfibrillar structure of type I collagen in situ
The fibrous collagens are ubiquitous in animals and form the structural basis of all
mammalian connective tissues, including those of the heart, vasculature, skin, cornea …
mammalian connective tissues, including those of the heart, vasculature, skin, cornea …
[HTML][HTML] Molecular level detection and localization of mechanical damage in collagen enabled by collagen hybridizing peptides
Mechanical injury to connective tissue causes changes in collagen structure and material
behaviour, but the role and mechanisms of molecular damage have not been established. In …
behaviour, but the role and mechanisms of molecular damage have not been established. In …
Building collagen molecules, fibrils, and suprafibrillar structures
DJS Hulmes - Journal of structural biology, 2002 - Elsevier
Fibril-forming collagens are synthesized in precursor form, procollagens, with N-and C-
terminal propeptide extensions. The C-propeptides direct chain association during …
terminal propeptide extensions. The C-propeptides direct chain association during …
[HTML][HTML] The role of collagen crosslinks in ageing and diabetes-the good, the bad, and the ugly
JG Snedeker, A Gautieri - Muscles, ligaments and tendons journal, 2014 - ncbi.nlm.nih.gov
The non-enzymatic reaction of proteins with glucose (glycation) is a topic of rapidly growing
importance in human health and medicine. There is increasing evidence that this reaction …
importance in human health and medicine. There is increasing evidence that this reaction …
Collagen fibril assembly and function
Collagen fibrils are the major mechanical component in the extracellular matrix of a broad
range of multicellular animals from echinoderms to vertebrates where they provide a stable …
range of multicellular animals from echinoderms to vertebrates where they provide a stable …
Fibrillar collagens
Fibrillar collagens (types I, II, III, V, XI, XXIV and XXVII) constitute a sub-group within the
collagen family (of which there are 28 types in humans) whose functions are to provide three …
collagen family (of which there are 28 types in humans) whose functions are to provide three …