Therapeutic drug monitoring (TDM) is the quantification and interpretation of drug
concentrations in blood to optimize pharmacotherapy. It considers the interindividual …

Therapeutic drug monitoring (TDM) plays an important role in ensuring optimal drug therapy
and has become increasingly important in clinical practice. In the first part of this review …

Women with epilepsy (WWE) wishing for a child represent a highly relevant subgroup of
epilepsy patients. The treating epileptologist needs to delineate the epilepsy syndrome and …

Acute, symptomatic seizures or epilepsy may complicate the course of hepatic disease.
Choosing the most appropriate antiepileptic drug in this setting represents a difficult …

Anti-epileptic drugs (AEDs) are an important group of drugs of several generations, ranging
from the oldest phenobarbital (1912) to the most recent cenobamate (2019). Cannabidiol …

Epilepsy is a widely diffused neurological disorder including a heterogeneous range of
syndromes with different aetiology, severity and prognosis. Pharmacological treatments are …

Precision medicine, particularly therapeutic drug monitoring (TDM), is essential for
optimizing drug dosage and minimizing toxicity. However, current TDM methods have …

Trichinellosis is a worldwide zoonotic disease. The majority of currently available anti-
trichinellosis medications exhibit inadequate efficacy. The efficacy of a natively prepared …

Population factors such as age, gender, ethnicity, genotype and disease state can cause
inter-individual variability in pharmacokinetic (PK) profile of drugs. Primarily, this variability …

Difluoromethyl groups possess specific steric and electronic properties due to their slightly
acidic C–H bonds and the natural characteristics of fluorine atoms, which allow them to act …