[HTML][HTML] Atrial cardiomyopathy: pathophysiology and clinical consequences

A Goette, U Lendeckel - Cells, 2021 - mdpi.com
Around the world there are 33.5 million patients suffering from atrial fibrillation (AF) with an
annual increase of 5 million cases. Most AF patients have an established form of an atrial …

Comprehensive comparison of stroke risk score performance: a systematic review and meta-analysis among 6 267 728 patients with atrial fibrillation

VHW van der Endt, J Milders, BBL Penning de Vries… - Europace, 2022 - academic.oup.com
Aims Multiple risk scores to predict ischaemic stroke (IS) in patients with atrial fibrillation (AF)
have been developed. This study aims to systematically review these scores, their …

MicroRNA signatures differentiate preserved from reduced ejection fraction heart failure

CJ Watson, SK Gupta, E O'Connell… - European journal of …, 2015 - Wiley Online Library
Aims Differentiation of heart failure with reduced (HFrEF) or preserved (HFpEF) ejection
fraction independent of echocardiography is challenging in the community. Diagnostic …

MicroRNAs in Atrial Fibrillation: mechanisms, vascular implications, and therapeutic potential

EP Vardas, P Theofilis, E Oikonomou, PE Vardas… - Biomedicines, 2024 - mdpi.com
Atrial fibrillation (AFib), the most prevalent arrhythmia in clinical practice, presents a growing
global health concern, particularly with the aging population, as it is associated with …

miR-146a is a pivotal regulator of neutrophil extracellular trap formation promoting thrombosis

AB Arroyo, MP Fernández-Pérez, A Del Monte… - …, 2020 - pmc.ncbi.nlm.nih.gov
Neutrophil extracellular traps (NET) induce a procoagulant response linking inflammation
and thrombosis. Low levels of miR-146a, a brake of inflammatory response, are involved in …

Circulating miR-26a-1, miR-146a and miR-199a-1 are potential candidate biomarkers for acute myocardial infarction

S Xue, W Zhu, D Liu, Z Su, L Zhang, Q Chang, P Li - Molecular Medicine, 2019 - Springer
Background Acute myocardial infarction (AMI) was considered to be one of the major causes
of morbidity and mortality worldwide. In order to manage the acute myocardial infarction …

Inflammatory microRNAs in cardiovascular pathology: another brick in the wall

L Zapata-Martínez, S Águila… - Frontiers in …, 2023 - frontiersin.org
The regulatory role of microRNAs (miRNAs) is mainly mediated by their effect on protein
expression and is recognized in a multitude of pathophysiological processes. In recent …

MiR-146a regulates neutrophil extracellular trap formation that predicts adverse cardiovascular events in patients with atrial fibrillation

AB Arroyo, AM de Los Reyes-García… - … , and vascular biology, 2018 - ahajournals.org
Objective—Atrial fibrillation (AF) patients experience adverse cardiovascular events (ACEs)
despite anticoagulant therapy. We reported that rs2431697 of miR-146a, a negative …

[HTML][HTML] miR-146a-5p, miR-223-3p and miR-142-3p as potential predictors of major adverse cardiac events in young patients with acute ST Elevation myocardial …

AI Scărlătescu, T Barbălată, AV Sima, C Stancu… - Diagnostics, 2022 - mdpi.com
Acute ST elevation myocardial infarction (STEMI) remains a leading cause of morbidity and
mortality worldwide despite continuous advances in diagnostic, prognostic and therapeutic …

Diagnostic and theranostic microRNAs in the pathogenesis of atherosclerosis

S Shoeibi - Acta Physiologica, 2020 - Wiley Online Library
MicroRNAs (miRNAs) are a group of small single strand and noncoding RNAs that regulate
several physiological and molecular signalling pathways. Alterations of miRNA expression …