Population-specific common SNPs reflect demographic histories and highlight regions of genomic plasticity with functional relevance
Background Population differentiation is the result of demographic and evolutionary forces.
Whole genome datasets from the 1000 Genomes Project (October 2012) provide an …
Whole genome datasets from the 1000 Genomes Project (October 2012) provide an …
Whole-genome sequence analyses of Western Central African Pygmy hunter-gatherers reveal a complex demographic history and identify candidate genes under …
African Pygmies practicing a mobile hunter-gatherer lifestyle are phenotypically and
genetically diverged from other anatomically modern humans, and they likely experienced …
genetically diverged from other anatomically modern humans, and they likely experienced …
[HTML][HTML] Heterogeneous distribution of SNPs in the human genome: microsatellites as predictors of nucleotide diversity and divergence
MA Varela, W Amos - Genomics, 2010 - Elsevier
Understanding the forces that govern the distribution of single nucleotide polymorphisms is
vital for many of their applications. Here we conducted a systematic search to quantify how …
vital for many of their applications. Here we conducted a systematic search to quantify how …
Phenotypic differentiation of Streptococcus pyogenes populations is induced by recombination-driven gene-specific sweeps
Genomic recombination plays an important role in driving adaptive evolution and population
differentiation in bacteria. However, controversy exists as to the effects of recombination on …
differentiation in bacteria. However, controversy exists as to the effects of recombination on …
Molecular adaptation in flowering and symbiotic recognition pathways: insights from patterns of polymorphism in the legume Medicago truncatula
S De Mita, N Chantret, K Loridon, J Ronfort… - BMC Evolutionary …, 2011 - Springer
Background We studied patterns of molecular adaptation in the wild Mediterranean legume
Medicago truncatula. We focused on two phenotypic traits that are not functionally linked …
Medicago truncatula. We focused on two phenotypic traits that are not functionally linked …
Experiments with the site frequency spectrum
Evaluating the likelihood function of parameters in highly-structured population genetic
models from extant deoxyribonucleic acid (DNA) sequences is computationally prohibitive …
models from extant deoxyribonucleic acid (DNA) sequences is computationally prohibitive …
[HTML][HTML] Molecular epigenetics, chromatin, and NeuroAIDS/HIV: translational implications
P Shapshak, F Chiappelli, D Commins, E Singer… - …, 2008 - ncbi.nlm.nih.gov
We describe current research that applies epigenetics to a novel understanding of the
immuno-neuropathogenesis of HIV-1 viral infection and NeuroAIDS. We propose the …
immuno-neuropathogenesis of HIV-1 viral infection and NeuroAIDS. We propose the …
Dependency between protein–protein interactions and protein variability and evolutionary rates in vertebrates: Observed relationships and stochastic modeling
X Wang, S Branciamore, G Gogoshin… - Journal of Molecular …, 2019 - Springer
Recent developments in sequencing and growth of bioinformatics resources provide us with
vast depositories of protein network and single nucleotide polymorphism data. It allows us to …
vast depositories of protein network and single nucleotide polymorphism data. It allows us to …
Scale invariant correlations between genes and SNPs on human chromosome 1 reveal potential evolutionary mechanisms
WS Kendal - Journal of theoretical biology, 2007 - Elsevier
The local density of gene structures and single nucleotide polymorphisms (SNPs) along
human chromosomes appears inhomogeneous. In chromosome 1, the density patterns from …
human chromosomes appears inhomogeneous. In chromosome 1, the density patterns from …
Statistical inference and modelling for nosocomial infections and the incorporation of whole genome sequence data
CJ Worby - 2013 - eprints.nottingham.ac.uk
Healthcare-associated infections (HCAIs) remain a problem worldwide, and can cause
severe illness and death. The increasing level of antibiotic resistance among bacteria that …
severe illness and death. The increasing level of antibiotic resistance among bacteria that …