Prospects, advances and biological applications of MOF-based platform for the treatment of lung cancer

Y Deng, M Guo, L Zhou, Y Huang, S Srivastava… - Biomaterials …, 2024 - pubs.rsc.org
Nowadays in our society, lung cancer is exhibiting a high mortality rate and threat to human
health. Conventional diagnostic techniques used in the field of lung cancer often necessitate …

Nanomaterials in tumor immunotherapy: new strategies and challenges

X Zhu, S Li - Molecular Cancer, 2023 - Springer
Tumor immunotherapy exerts its anti-tumor effects by stimulating and enhancing immune
responses of the body. It has become another important modality of anti-tumor therapy with …

Nanoarchitecture-integrated hydrogel systems toward therapeutic applications

H Zhu, J Zheng, XY Oh, CY Chan, BQL Low, JQ Tor… - ACS …, 2023 - ACS Publications
Hydrogels, as one of the most feasible soft biomaterials, have gained considerable attention
in therapeutic applications by virtue of their tunable properties including superior patient …

Biomaterials for in situ cell therapy

C Wang, S Wang, DD Kang, Y Dong - BMEMat, 2023 - Wiley Online Library
Cell therapy has revolutionized the treatment of various diseases, such as cancers, genetic
disorders, and autoimmune diseases. Currently, most cell therapy products rely on ex vivo …

Nanoparticles in tumor microenvironment remodeling and cancer immunotherapy

Q Lu, D Kou, S Lou, M Ashrafizadeh, AR Aref… - Journal of Hematology & …, 2024 - Springer
Cancer immunotherapy and vaccine development have significantly improved the fight
against cancers. Despite these advancements, challenges remain, particularly in the clinical …

Immunostimulant hydrogel-guided tumor microenvironment reprogramming to efficiently potentiate macrophage-mediated cellular phagocytosis for systemic cancer …

JL Liang, XK **, GF Luo, SM Zhang, QX Huang… - ACS …, 2023 - ACS Publications
Macrophage-mediated cellular phagocytosis (MMCP) plays a critical role in conducting
antitumor immunotherapy but is usually impaired by the intrinsic phagocytosis evading …

Hydrogel drug delivery systems for minimally invasive local immunotherapy of cancer

AS Mikhail, R Morhard, M Mauda-Havakuk… - Advanced Drug Delivery …, 2023 - Elsevier
Although systemic immunotherapy has achieved durable responses and improved survival
for certain patients and cancer types, low response rates and immune system-related …

Injectable hydrogels for personalized cancer immunotherapies

N Mohaghegh, A Ahari, F Zehtabi, C Buttles, S Davani… - Acta Biomaterialia, 2023 - Elsevier
The field of cancer immunotherapy has shown significant growth, and researchers are now
focusing on effective strategies to enhance and prolong local immunomodulation. Injectable …

Polysaccharide-based tumor microenvironment-responsive drug delivery systems for cancer therapy

Q Wu, Y Hu, B Yu, H Hu, FJ Xu - Journal of Controlled Release, 2023 - Elsevier
The biochemical indicators of tumor microenvironment (TME) that are different from normal
tissues provide the possibility for constructing intelligent drug delivery systems (DDSs) …

Hydrogel-based platforms for site-specific doxorubicin release in cancer therapy

C Zang, Y Tian, Y Tang, M Tang, D Yang… - Journal of Translational …, 2024 - Springer
Hydrogels are promising candidates for the delivery of therapeutics in the treatment of
human cancers. Regarding to the biocomaptiiblity, high drug and encapsulation efficacy and …