[HTML][HTML] High-throughput proteomics: a methodological mini-review

M Cui, C Cheng, L Zhang - Laboratory investigation, 2022 - Elsevier
Proteomics plays a vital role in biomedical research in the post-genomic era. With the
technological revolution and emerging computational and statistic models, proteomic …

Single-cell sequencing-based technologies will revolutionize whole-organism science

E Shapiro, T Biezuner, S Linnarsson - Nature Reviews Genetics, 2013 - nature.com
The unabated progress in next-generation sequencing technologies is fostering a wave of
new genomics, epigenomics, transcriptomics and proteomics technologies. These …

Homogenous 96-plex PEA immunoassay exhibiting high sensitivity, specificity, and excellent scalability

E Assarsson, M Lundberg, G Holmquist, J Björkesten… - PloS one, 2014 - journals.plos.org
Medical research is develo** an ever greater need for comprehensive high-quality data
generation to realize the promises of personalized health care based on molecular …

Aptamer-based multiplexed proteomic technology for biomarker discovery

L Gold, D Ayers, J Bertino, C Bock, A Bock, E Brody… - Nature …, 2010 - nature.com
Interrogation of the human proteome in a highly multiplexed and efficient manner remains a
coveted and challenging goal in biology. We present a new aptamer-based proteomic …

Homogeneous antibody-based proximity extension assays provide sensitive and specific detection of low-abundant proteins in human blood

M Lundberg, A Eriksson, B Tran… - Nucleic acids …, 2011 - academic.oup.com
Convenient and well-performing protein detection methods for a wide range of targets are in
great demand for biomedical research and future diagnostics. Assays without the need for …

Electrochemical detection of nucleic acids, proteins, small molecules and cells using a DNA-nanostructure-based universal biosensing platform

M Lin, P Song, G Zhou, X Zuo, A Aldalbahi, X Lou… - nature protocols, 2016 - nature.com
The occurrence and prognosis of many complex diseases, such as cancers, is associated
with the variation of various molecules, including DNA at the genetic level, RNA at the …

Exploration of Nanoparticle-Mediated Photothermal Effect of TMB-H2O2 Colorimetric System and Its Application in a Visual Quantitative Photothermal Immunoassay

G Fu, ST Sanjay, W Zhou, RA Brekken… - Analytical …, 2018 - ACS Publications
The exploration of new physical and chemical properties of materials and their innovative
application in different fields are of great importance to advance analytical chemistry …

DNA-mediated homogeneous binding assays for nucleic acids and proteins

H Zhang, F Li, B Dever, XF Li, XC Le - Chemical reviews, 2013 - ACS Publications
The detection of nucleic acids and proteins is fundamental for studying their functions and
for the development of molecular diagnostics. These molecules carry out most biological …

Nanotechnology and cancer

JR Heath, ME Davis - Annu. Rev. Med., 2008 - annualreviews.org
The biological picture of cancer is rapidly advancing from models built from
phenomenological descriptions to network models derived from systems biology, which can …

Aptamers and the next generation of diagnostic reagents

V Thiviyanathan, DG Gorenstein - PROTEOMICS–Clinical …, 2012 - Wiley Online Library
Antibodies have been extensively used as capture and detection reagents in diagnostic
applications of proteomics‐based technologies. Proteomic assays need high sensitivity and …