The native environment of membrane proteins is complex and scientists have felt the need
to simplify it to reduce the number of varying parameters. However, experimental problems …

Phospholamban (PLN) and sarcolipin (SLN) are two single-pass membrane proteins that
regulate Ca2+-ATPase (SERCA), an ATP-driven pump that translocates calcium ions into …

Phospholamban (PLN) is an essential regulator of cardiac muscle contractility. The
homopentameric assembly of PLN is the reservoir for active monomers that, upon …

α-Helical membrane proteins fulfill many vital roles in all living cells and constitute the
majority of drug targets. However, their relevance is in no way paralleled by our current …

Phospholamban (PLN), a single-pass membrane protein, regulates heart muscle contraction
and relaxation by reversible inhibition of the sarco (endo) plasmic reticulum Ca-ATPase …

Phospholamban (PLB) is a 52-amino acid integral membrane protein that helps to regulate
the flow of Ca2+ ions in cardiac muscle cells. Recent structural studies on the PLB pentamer …

Wild-type phospholamban (WT-PLB), a Ca2+-ATPase (SERCA) regulator in the
sarcoplasmic reticulum membrane, was studied using TOAC nitroxide spin labeling …

We have applied a bifunctional spin label and EPR spectroscopy to determine membrane
protein structural topology in magnetically-aligned bicelles, using monomeric …

Phospholamban (PLB) is an integral membrane protein regulating Ca2+ transport through
inhibitory interaction with sarco (endo) plasmic reticulum calcium ATPase (SERCA). The …

Divalent cations, especially Ca2+ and Mg2+, play a vital role in the function of biomolecules
and making them important to be constituents in samples for in vitro biophysical and …