Controlled drug delivery vehicles for cancer treatment and their performance

S Senapati, AK Mahanta, S Kumar… - Signal transduction and …, 2018 - nature.com
Although conventional chemotherapy has been successful to some extent, the main
drawbacks of chemotherapy are its poor bioavailability, high-dose requirements, adverse …

Block copolymer micelles in nanomedicine applications

H Cabral, K Miyata, K Osada, K Kataoka - Chemical reviews, 2018 - ACS Publications
Polymeric micelles are demonstrating high potential as nanomedicines capable of
controlling the distribution and function of loaded bioactive agents in the body, effectively …

Rethinking cancer nanotheranostics

H Chen, W Zhang, G Zhu, J **e, X Chen - Nature Reviews Materials, 2017 - nature.com
Advances in nanoparticle synthesis and engineering have produced nanoscale agents
affording both therapeutic and diagnostic functions that are often referred to by the …

Nanomaterials for theranostics: recent advances and future challenges

EK Lim, T Kim, S Paik, S Haam, YM Huh… - Chemical reviews, 2015 - ACS Publications
In 2004, the US Food and Drug Administration (FDA) released an important report entitled
“Innovation/Stagnation: Challenge and Opportunity on the Critical Path to New Medical …

Progress of drug-loaded polymeric micelles into clinical studies

H Cabral, K Kataoka - Journal of Controlled Release, 2014 - Elsevier
Targeting tumors with long-circulating nano-scaled carriers is a promising strategy for
systemic cancer treatment. Compared with free small therapeutic agents, nanocarriers can …

Targeting and delivery of platinum-based anticancer drugs

X Wang, Z Guo - Chemical Society Reviews, 2013 - pubs.rsc.org
Platinum-based anticancer drugs occupy a crucial role in the treatment of various malignant
tumours. However, the efficacy and applicability of platinum drugs are heavily restricted by …

What blocks more anticancer platinum complexes from experiment to clinic: Major problems and potential strategies from drug design perspectives

K Peng, BB Liang, W Liu, ZW Mao - Coordination Chemistry Reviews, 2021 - Elsevier
Encouraged by the worldwide success of cisplatin in the field of cancer chemotherapy,
intensive works have been conducted to explore more platinum coordination complexes as …

Nanotheranostics for personalized medicine

S Mura, P Couvreur - Advanced drug delivery reviews, 2012 - Elsevier
The application of nanotechnology in the biomedical field, known as nanomedicine, has
gained much interest in the recent past, as versatile strategy for selective drug delivery and …

Polymeric micelles for nano-scale drug delivery

K Miyata, RJ Christie, K Kataoka - Reactive and Functional Polymers, 2011 - Elsevier
This review describes the design of polymeric micelles from block copolymers and their
performances as nano-scale drug delivery systems, with emphasis on our recent work. The …

[HTML][HTML] Theranostic polymeric nanoparticles as a new approach in cancer therapy and diagnosis: a review

SM Hosseini, J Mohammadnejad, S Salamat… - Materials Today …, 2023 - Elsevier
The theranostic term is a revolutionary topic in cancer treatment, combining therapeutic and
diagnostic. Theranostic provides an opportunity for diagnosis and response assessment …