Interactions between metal oxides and biomolecules: from fundamental understanding to applications

MJ Limo, A Sola-Rabada, E Boix, V Thota… - Chemical …, 2018 - ACS Publications
Metallo-oxide (MO)-based bioinorganic nanocomposites promise unique structures,
physicochemical properties, and novel biochemical functionalities, and within the past …

Non-viral nanocarriers for intracellular delivery of microRNA therapeutics

Z Bai, J Wei, C Yu, X Han, X Qin, C Zhang… - Journal of Materials …, 2019 - pubs.rsc.org
MicroRNAs are small regulatory noncoding RNAs that regulate various biological processes
associated with neurological disorders, cardiovascular diseases, cancer and viral infection …

Engineered Design of a Mesoporous Silica Nanoparticle-Based Nanocarrier for Efficient mRNA Delivery in Vivo

S Dong, Z Feng, R Ma, T Zhang, J Jiang, Y Li… - Nano Letters, 2023 - ACS Publications
We have developed tailor-designed mesoporous silica nanoparticles (MSNPs) specifically
for delivering mRNA. Our unique assembly protocol involves premixing mRNA with a …

Nanoparticle mediated RNA delivery for wound healing

E Kolanthai, Y Fu, U Kumar, B Babu… - Wiley …, 2022 - Wiley Online Library
Wound healing is a complicated physiological process that comprises various steps,
including hemostasis, inflammation, proliferation, and remodeling. The wound healing …

Recent applications of the combination of mesoporous silica nanoparticles with nucleic acids: development of bioresponsive devices, carriers and sensors

RR Castillo, A Baeza, M Vallet-Regí - Biomaterials science, 2017 - pubs.rsc.org
The discovery and control of the biological roles mediated by nucleic acids have turned
them into a powerful tool for the development of advanced biotechnological materials. Such …

Recent advances in RNA therapeutics and RNA delivery systems based on nanoparticles

H Shin, SJ Park, Y Yim, J Kim, C Choi… - Advanced …, 2018 - Wiley Online Library
Recently, there have been significant advances in the field of RNA‐based therapeutics
harnessing exogenous RNAs including small interfering RNA (siRNA), microRNA (miRNA) …

[HTML][HTML] Mesoporous silica nanoparticles as carriers for intracellular delivery of nucleic acids and subsequent therapeutic applications

W Cha, R Fan, Y Miao, Y Zhou, C Qin, X Shan, X Wan… - Molecules, 2017 - mdpi.com
Nucleic acids, including DNA, microRNA (miRNA), small interfering RNA (siRNA), and
antisense oligonucleotide (ASO), are powerful gene regulators, which have been …

[HTML][HTML] Biomedical applications of solid-binding peptides and proteins

N Alvisi, R de Vries - Materials today Bio, 2023 - Elsevier
Over the past decades, solid-binding peptides (SBPs) have found multiple applications in
materials science. In non-covalent surface modification strategies, solid-binding peptides …

Nanoparticles designed to regulate tumor microenvironment for cancer therapy

M Li, F Zhang, Y Su, J Zhou, W Wang - Life sciences, 2018 - Elsevier
Increasing understanding in tumor pathology reveals that tumor microenvironment (TME),
which supports tumor progression and poses barriers for available therapies, takes a great …

Formulation of mesoporous silica nanoparticles for controlled release of antimicrobials for stone preventive conservation

A Presentato, F Armetta, A Spinella… - Frontiers in …, 2020 - frontiersin.org
The biotic deterioration of artifacts of archaeological and artistic interest mostly relies on the
action of microorganisms capable of thriving under the most disparate environmental …