Physical activity, by definition, is any skeletal muscle body movement that results in energy
expenditure. In the last few decades, a plethora of scientific evidences have accumulated …

Due to the heterogeneous nature of the disease, it is a challenge to capture disease activity
of multiple sclerosis (MS) in a reliable and valid way. Therefore, it can be difficult to assess …

Background Secondary progressive multiple sclerosis, for which no satisfactory treatment
presently exists, accounts for most of the disability in patients with multiple sclerosis …

Книга посвящена вопросам использования опросников, тестов и шкал для оценки
состояния неврологических больных и определения эффективности лечения …

Objective: To develop a patient-based measure of walking ability in MS. Methods: Twelve
items describing the impact of MS on walking (12-Item MS Walking Scale [MSWS-12]) were …

Background: There is no consensus method for determining progression of disability in
patients with multiple sclerosis (MS) when each patient has had only a single assessment in …

Objectives In this monograph we examine the added value of new psychometric methods
(Rasch measurement and Item Response Theory) over traditional psychometric approaches …

Summary About 10–15% of patients with multiple sclerosis (MS) present with gradually
increasing neurological disability, a disorder known as primary-progressive multiple …

Background Daclizumab high-yield process (HYP) is a humanized monoclonal antibody that
binds to CD25 (alpha subunit of the interleukin-2 receptor) and modulates interleukin-2 …

Physical activity has been associated with a small improvement in quality of life (QOL)
among those with multiple sclerosis (MS). This relationship may be indirect and operate …