Exhaled breath contains thousand metabolites and volatile organic compounds (VOCs) that
originated from both respiratory tract and internal organ systems and their microbiomes …

Pathogenic microorganisms produce numerous metabolites, including volatile organic
compounds (VOCs). Monitoring these metabolites in biological matrices (eg, urine, blood, or …

Background Severe asthma is a heterogeneous condition, as shown by independent cluster
analyses based on demographic, clinical, and inflammatory characteristics. A next step is to …

Despite the tremendous success, pitfalls have been observed in every step of a clinical
metabolomics workflow, which impedes the internal validity of the study. Furthermore, the …

The studies on the composition of the human microbiomes in healthy individuals, its
variability in the course of inflammation, infection, antibiotic therapy, diets and different …

Background Early and accurate recognition of respiratory pathogens is crucial to prevent
increased risk of mortality in critically ill patients. Microbial-derived volatile organic …

Rationale: The early identification of children with poorly controlled asthma is imperative for
optimizing treatment strategies. The analysis of exhaled volatile organic compounds (VOCs) …

An analysis of exhaled breath enables specialists to noninvasively monitor biochemical
processes and to determine any pathological state in the human body. Breath analysis holds …

Background & aims Analysis of volatile organic compounds (VOCs) in exhaled
breath,'volatomics', provides opportunities for non-invasive biomarker discovery and novel …

Many patients with chronic obstructive lung disease (COPD) experience exacerbations. The
diagnosis of an exacerbation is solely based on symptoms. We hypothesized that exhaled …