Tight junctions (TJs) are intercellular junctions critical for building the epithelial barrier and
maintaining epithelial polarity. The claudin family of membrane proteins play central roles in …

Blood vessels are critical to deliver oxygen and nutrients to tissues and organs throughout
the body. The blood vessels that vascularize the central nervous system (CNS) possess …

Oligodendrocytes generate multiple layers of myelin membrane around axons of the central
nervous system to enable fast and efficient nerve conduction. Until recently, saltatory nerve …

The dura, arachnoid and pia mater, as the constituent layers of the meninges, along with
cerebrospinal fluid in the subarachnoid space and ventricles, are essential protectors of the …

Blood vessels are critical to deliver oxygen and nutrients to all of the tissues and organs
throughout the body. The blood vessels that vascularize the central nervous system (CNS) …

Meninges cover the surface of the brain and spinal cord and contribute to protection and
immune surveillance of the central nervous system (CNS). How the meningeal layers …

Myelinated nerve fibers have evolved to enable fast and efficient transduction of electrical
signals in the nervous system. To act as an electric insulator, the myelin sheath is formed as …

Spermatogenesis is the cellular process by which spermatogonia develop into mature
spermatids within seminiferous tubules, the functional unit of the mammalian testis, under …

Claudins are tight junction membrane proteins that are expressed in epithelia and
endothelia and form paracellular barriers and pores that determine tight junction …

Unique intercellular junctional complexes between the central nervous system (CNS)
microvascular endothelial cells and the choroid plexus epithelial cells form the endothelial …