[HTML][HTML] Brain default-mode network dysfunction in addiction

R Zhang, ND Volkow - Neuroimage, 2019‏ - Elsevier
Aberrant patterns of brain functional connectivity in the default mode network (DMN) have
been observed across different classes of substance use disorder (SUD) and are associated …

Altered GABA-mediated information processing and cognitive dysfunctions in depression and other brain disorders

T Prévot, E Sibille - Molecular psychiatry, 2021‏ - nature.com
Cognitive dysfunctions, including impaired attention, learning, memory, planning and
problem solving, occur in depressive episodes, often persist during remission, predict …

Depressive rumination, the default-mode network, and the dark matter of clinical neuroscience

JP Hamilton, M Farmer, P Fogelman, IH Gotlib - Biological psychiatry, 2015‏ - Elsevier
The intuitive association between self-focused rumination in major depressive disorder
(MDD) and the self-referential operations performed by the brain's default-mode network …

Somatostatin-positive gamma-aminobutyric acid interneuron deficits in depression: cortical microcircuit and therapeutic perspectives

C Fee, M Banasr, E Sibille - Biological psychiatry, 2017‏ - Elsevier
The functional integration of external and internal signals forms the basis of information
processing and is essential for higher cognitive functions. This occurs in finely tuned cortical …

Causal interactions between fronto-parietal central executive and default-mode networks in humans

AC Chen, DJ Oathes, C Chang, T Bradley… - Proceedings of the …, 2013‏ - pnas.org
Information processing during human cognitive and emotional operations is thought to
involve the dynamic interplay of several large-scale neural networks, including the fronto …

How is our self related to midline regions and the default-mode network?

P Qin, G Northoff - Neuroimage, 2011‏ - Elsevier
The problem of the self has been of increasing interest in recent neuroscience. Brain
imaging studies have raised the question of whether neural activity in cortical midline …

A Guide to the Metabolic Pathways and Function of Metabolites Observed in Human Brain 1H Magnetic Resonance Spectra

CD Rae - Neurochemical research, 2014‏ - Springer
The current knowledge of the normal biochemistry of compounds that give rise to
resonances in human brain proton magnetic resonance spectra measureable at readily …

Frontocingulate dysfunction in depression: toward biomarkers of treatment response

DA Pizzagalli - Neuropsychopharmacology, 2011‏ - nature.com
Increased rostral anterior cingulate cortex (rACC) activity has emerged as a promising
predictor of treatment response in depression, but neither the reliability of this relationship …

Default-mode brain dysfunction in mental disorders: a systematic review

SJ Broyd, C Demanuele, S Debener, SK Helps… - … & biobehavioral reviews, 2009‏ - Elsevier
In this review we are concerned specifically with the putative role of the default-mode
network (DMN) in the pathophysiology of mental disorders. First, we define the DMN concept …

In vivo magnetic resonance spectroscopy of GABA: a methodological review

NAJ Puts, RAE Edden - Progress in nuclear magnetic resonance …, 2012‏ - Elsevier
Conclusion MRS has become established as a robust and powerful tool for the investigation
of the inhibitory neurotransmitter GABA. This is a significant success, given the significant …