Effect of copper deficiency on prenatal development and pregnancy outcome

CL Keen, JY Uriu-Hare, SN Hawk… - The American journal of …, 1998 - Elsevier
Copper deficiency during embryonic and fetal development can result in numerous gross
structural and biochemical abnormalities. Such a deficiency can arise through a variety of …

Copper metabolism and inherited coppertransport disorders: molecular mechanisms, screening, and treatment

H Kodama, C Fujisawa - Metallomics, 2009 - academic.oup.com
In this review, we discuss genetic disorders involving altered coppermetabolism, particularly
in relation to Menkes disease (MD), occipital horn syndrome (OHS), and Wilson's disease …

Cisplatin-induced loss of kidney copper and nephrotoxicity is ameliorated by single dose diethyldithiocarbamate, but not mesna

RS DeWoskin, JE Riviere - Toxicology and applied pharmacology, 1992 - Elsevier
Platinum, copper, and zinc concentrations in kidney and liver were monitored following
administration of cis-diamminedichloroplatinum (Cisplatin, CDDP) alone or in combination …

Effect of copper and diethyldithiocarbamate combination therapy on the macular mouse, an animal model of Menkes disease

H Kodama, E Sato, YH Gu, K Shiga… - Journal of Inherited …, 2005 - Wiley Online Library
Menkes disease (MD) is a neurodegenerative disorder characterized by a copper deficiency
in the brain. It is caused by the defective intestinal absorption of copper resulting from a …

Recent advances in copper radiopharmaceuticals

G Hao, AN Singh, OK Oz, X Sun - Current …, 2011 - ingentaconnect.com
Copper has five radioisotopes (60Cu, 61Cu, 62Cu, 64Cu, and 67Cu) that can be used in
copper radiopharmaceuticals. These radioisotopes decay by mixed emissions of β+, β-, and …

Effect of sodium pyridinethione on the uptake and distribution of nickel, cadmium and zinc in pregnant and non-pregnant mice

S Jasim, H Tjälve - Toxicology, 1986 - Elsevier
Oral administration of sodium pyridinethione together with 63 Ni 2+, 109 Cd 2+ or 65 Zn 2+
to non-pregnant mice resulted in very markedly increased levels of the metals in several …

Oral cadmium chloride intoxication in mice: diethyldithiocarbamate enhances rather than alleviates acute toxicity

O Andersen, JB Nielsen, P Svendsen - Toxicology, 1988 - Elsevier
Diethyldithiocarbamate (DDC) is known to alleviate acute toxicity due to injection of
cadmium salts. However, when cadmium chloride was administered by the oral route, DDC …

Effect of thiram and dithiocarbamate pesticides on the gastrointestinal absorption and distribution of nickel in mice

K Borg, H Tjälve - Toxicology letters, 1988 - Elsevier
Oral administration of dimethyldithiocarbamate pesticides (ferbam, ziram or sodium
dimethyldithiocarbamate) or thiram together with nickel resulted in increased levels of the …

Prenatal treatment of mosaic mice (Atp7a mo-ms) mouse model for Menkes disease, with copper combined by dimethyldithiocarbamate (DMDTC)

M Lenartowicz, W Krzeptowski, P Koteja, K Chrząścik… - PLoS …, 2012 - journals.plos.org
Menkes disease is a fatal neurodegenerative disorder in infants caused by mutations in the
gene ATP7A which encodes a copper (Cu) transporter. Defects in ATP7A lead to …

Neo-Timm and selenium stainable glial cells of the rat telencephalon

IE Holm - Histochemistry, 1989 - Springer
Summary The Neo-Timm and selenium methods predominantly stain the neuropil of the rat
brain and have been found to visualize zinc in synaptic vesicles. A fraction of glial cells and …