Periodontal health and disease in the context of systemic diseases

G Isola, S Santonocito, SM Lupi, A Polizzi… - Mediators of …, 2023 - Wiley Online Library
During recent years, considerable progress has been made in understanding the
etiopathogenesis of periodontitis in its various forms and their interactions with the host …

Chronic inflammation in end-stage renal disease and dialysis

G Cobo, B Lindholm, P Stenvinkel - Nephrology Dialysis …, 2018 - academic.oup.com
Under normal conditions, inflammation is a protective and physiological response to various
harmful stimuli. However, in several chronic debilitating disorders, such as chronic kidney …

A metal-organic framework-based immunomodulatory nanoplatform for anti-atherosclerosis treatment

Z Xu, Z Wu, S Huang, K Ye, Y Jiang, J Liu, J Liu… - Journal of Controlled …, 2023 - Elsevier
Immunomodulatory therapy has become a promising method for the clinical treatment of
many diseases. Recently, pilot studies revealed that immunomodulatory therapy exhibited …

Defining dysbiosis for a cluster of chronic diseases

LJ Wilkins, M Monga, AW Miller - Scientific reports, 2019 - nature.com
The prevalence of many chronic diseases has increased over the last decades. It has been
postulated that dysbiosis driven by environmental factors such as antibiotic use is shifting …

Conceptual approaches to modulating antibody effector functions and circulation half-life

KO Saunders - Frontiers in immunology, 2019 - frontiersin.org
Antibodies and Fc-fusion antibody-like proteins have become successful biologics
developed for cancer treatment, passive immunity against infection, addiction, and …

[HTML][HTML] Immune evasion in cancer: Mechanistic basis and therapeutic strategies

DS Vinay, EP Ryan, G Pawelec, WH Talib… - Seminars in cancer …, 2015 - Elsevier
Cancer immune evasion is a major stumbling block in designing effective anticancer
therapeutic strategies. Although considerable progress has been made in understanding …

HBXIP-elevated methyltransferase METTL3 promotes the progression of breast cancer via inhibiting tumor suppressor let-7g

X Cai, X Wang, C Cao, Y Gao, S Zhang, Z Yang, Y Liu… - Cancer letters, 2018 - Elsevier
Abstract Methyltransferase-like 3 (METTL3) is involved in RNA metabolism through N6-
methyladenosine (m 6 A) modification. However, whether METTL3 participates in the …

Regulation and targeting of SREBP-1 in hepatocellular carcinoma

F Su, A Koeberle - Cancer and Metastasis Reviews, 2024 - Springer
Hepatocellular carcinoma (HCC) is an increasing burden on global public health and is
associated with enhanced lipogenesis, fatty acid uptake, and lipid metabolic …

[HTML][HTML] The role of immune cells in breast tissue and immunotherapy for the treatment of breast cancer

SL Goff, DN Danforth - Clinical breast cancer, 2021 - Elsevier
Immune cells are present in normal breast tissue and in breast carcinoma. The nature and
distribution of the immune cell subtypes in these tissues are reviewed to promote a better …

InnateDB: systems biology of innate immunity and beyond—recent updates and continuing curation

K Breuer, AK Foroushani, MR Laird… - Nucleic acids …, 2013 - academic.oup.com
Abstract InnateDB (http://www. innatedb. com) is an integrated analysis platform that has
been specifically designed to facilitate systems-level analyses of mammalian innate …