Caspase-9 as a therapeutic target for treating cancer

B Kim, SK Srivastava, SH Kim - Expert opinion on therapeutic …, 2015 - Taylor & Francis
Introduction: Caspase-9 is the apoptotic initiator protease of the intrinsic or mitochondrial
apoptotic pathway, which is activated at multi-protein activation platforms. Its activation is …

Natural products against cancer angiogenesis

EB Khalid, ELMELK Ayman, H Rahman, G Abdelkarim… - Tumor Biology, 2016 - Springer
The process of angiogenesis is quite well-known nowadays. Some medicines and extracts
affecting this process are already used routinely in supporting the conventional treatment of …

Nanostructured lipid carriers enhance the bioavailability and brain cancer inhibitory efficacy of curcumin both in vitro and in vivo

Y Chen, L Pan, M Jiang, D Li, L ** - Drug Delivery, 2016 - Taylor & Francis
Brain cancer is a kind of tough carcinoma because the blood–brain barrier (BBB) remains a
formidable obstacle in medicine. Curcumin (Cur) was determined to have anticancer …

Cucurmin, anticancer, & antitumor perspectives: A comprehensive review

M Imran, A Ullah, F Saeed, M Nadeem… - Critical reviews in …, 2018 - Taylor & Francis
Cucurmin, a naturally yellow component isolated from turmeric, ability to prevent various life-
style related disorders. The current review article mainly emphasizes on different anticancer …

Betanin‐Enriched Red Beetroot (Beta vulgaris L.) Extract Induces Apoptosis and Autophagic Cell Death in MCF‐7 Cells

L Nowacki, P Vigneron, L Rotellini… - Phytotherapy …, 2015 - Wiley Online Library
Recent studies have pointed out the preventive role of beetroot extracts against cancers and
their cytotoxic activity on cancer cells. Among many different natural compounds, these …

Anticancer curcumin: natural analogues and structure-activity relationship

AP Gupta, S Khan, MM Manzoor, AK Yadav… - Studies in natural …, 2017 - Elsevier
Cancers have been found to be the leading causes of death worldwide, with 8.2 million
people dying in 2012 and approximately 14 million new cases reported. These cases are …

Sesamol induces human hepatocellular carcinoma cells apoptosis by impairing mitochondrial function and suppressing autophagy

Z Liu, B Ren, Y Wang, C Zou, Q Qiao, Z Diao, Y Mi… - Scientific Reports, 2017 - nature.com
Sesamol, a nutritional phenolic antioxidant compound enriched in sesame seeds, has been
shown to have potential anticancer activities. This study aims at characterizing the antitumor …

Herbal remedies use by breast cancer patients in the West Bank of Palestine

NA Jaradat, R Shawahna, AM Eid, R Al-Ramahi… - Journal of …, 2016 - Elsevier
Ethnopharmacological relevance Recent ethnopharmacological surveys showed that herbal
remedies are the most preferred modality of complementary and alternative medicine …

Natural inhibitors of PI3K/AKT signaling in breast cancer: emphasis on newly-discovered molecular mechanisms of action

Y Safdari, M Khalili, MA Ebrahimzadeh… - Pharmacological …, 2015 - Elsevier
Epidermal growth factor receptor (EGFR) plays a critical role in the initiation and progression
of a variety of human cancers, including breast cancer. An important signaling pathway …